{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T12:23:27Z","timestamp":1768566207620,"version":"3.49.0"},"reference-count":14,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,9,23]],"date-time":"2013-09-23T00:00:00Z","timestamp":1379894400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Vitiligo is an acquired disorder in which depigmented macules result from mostly autoimmune loss of melanocytes. The initiating process in vitiligo has still been uncertain. Here, we report the case of a 19\u2010year\u2010old man with undetermined\/unclassified vitiligo with a new periphery\u2010spreading vitiligo lesion on the right dorsal hand after rigorous sun exposure. Histopathological evaluation showed noticeable infiltration of <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>68<jats:sup>+<\/jats:sup> macrophages, moderate infiltration of <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>3<jats:sup>+<\/jats:sup> T cells, little infiltration of <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>8<jats:sup>+<\/jats:sup> T cells and <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>11c<jats:sup>+<\/jats:sup> myeloid dendritic cells, <jats:styled-content style=\"fixed-case\">HMB<\/jats:styled-content>45\/<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>11c double\u2010positive cells, and <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>elan\u2010A\/<jats:styled-content style=\"fixed-case\">MART<\/jats:styled-content>1<jats:sup>+<\/jats:sup> deposits in the dermis. We surmised that melanocyte\u2010derived deposits were mostly phagocytosed by <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>68<jats:sup>+<\/jats:sup> macrophages and were faintly phagocytosed by <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>11c<jats:sup>+<\/jats:sup> myeloid dendritic cells, referring distribution of <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>68<jats:sup>+<\/jats:sup> mononuclear cells and melanocyte biomarkers. Complete repigmentation was achieved following topical application of hydrocortisone butyrate propionate 0.1% ointment. We summarize that prompt clearance of debris by macrophages would be essential to an excellent prognosis of complete repigmentation.<\/jats:p>","DOI":"10.1111\/1346-8138.12263","type":"journal-article","created":{"date-parts":[[2013,10,11]],"date-time":"2013-10-11T21:48:25Z","timestamp":1381528105000},"page":"915-918","source":"Crossref","is-referenced-by-count":8,"title":["Role of macrophage infiltration in successful repigmentation in a new periphery\u2010spreading vitiligo lesion in a male <scp>J<\/scp>apanese patient"],"prefix":"10.1111","volume":"40","author":[{"given":"Naoki","family":"Oiso","sequence":"first","affiliation":[{"name":"Department of Dermatology Kinki University Faculty of Medicine Osaka\u2010Sayama Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Tanemura","sequence":"additional","affiliation":[{"name":"Department of Dermatology Integrated Medicine Osaka University Graduate School of Medicine Suita, Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yorihisa","family":"Kotobuki","sequence":"additional","affiliation":[{"name":"Department of Dermatology Integrated Medicine Osaka University Graduate School of Medicine Suita, Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masatomo","family":"Kimura","sequence":"additional","affiliation":[{"name":"Department of Pathology Kinki University Faculty of Medicine Osaka\u2010Sayama Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichiro","family":"Katayama","sequence":"additional","affiliation":[{"name":"Department of Dermatology Integrated Medicine Osaka University Graduate School of Medicine Suita, Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Kawada","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kinki University Faculty of Medicine Osaka\u2010Sayama Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-148X.2012.00997.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-148X.2011.00945.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.10.043"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2003.01743.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2010.00895.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2012.03.004"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar2966"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.21.120601.141040"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2048"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2009.06.018"},{"key":"e_1_2_6_12_1","first-page":"1219","article-title":"Presence of T cells and macrophages in inflammatory vitiligo skin parallels melanocyte disappearance","volume":"148","author":"Poole IC","year":"1996","journal-title":"Am J Pathol"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2009.03617.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12099"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201242468"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.12263","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.12263","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T17:25:46Z","timestamp":1696267546000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.12263"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,23]]},"references-count":14,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1111\/1346-8138.12263"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.12263","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,23]]}}}