{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T03:11:53Z","timestamp":1771902713607,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,11,8]],"date-time":"2013-11-08T00:00:00Z","timestamp":1383868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Actinic keratosis (<jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>) is a common precursor of sun\u2010related squamous cell carcinoma. <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content> is difficult to be differentiated from other malignancies with the naked eyes. Dermoscopic features of <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content> were previously described in some studies, but not extensively investigated. We investigated the dermoscopic features of <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content> in Asians and assessed dermoscopy as a post\u2010treatment monitoring tool of <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>. We retrospectively examined 34 <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content> lesions which had been diagnosed by histology. The changes of dermoscopic features and histopathological findings were assessed in all these lesions before and after treatment. Before treatment, 18 lesions were pigmented and 16 lesions were non\u2010pigmented <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content> dermoscopically. The frequent dermoscopic features of <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content> were keratin\/scales (79.4%), red pseudonetwork (73.5%), targetoid\u2010like appearance (55.9%), rosette sign (38.2%) and absent fissures\/ridges, crypts and milia\u2010like cysts. All the lesions had been treated with either photodynamic therapy, cryotherapy or 5% imiquimod cream. After treatment, dermoscopic features of 33 <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content> lesions were decreased or disappeared, and skin biopsies confirmed that atypical keratinocytes disappeared. One lesion showed accentuated and new dermoscopic features after treatment, and skin biopsy also showed progressing squamous cell carcinoma. In conclusion, scales, red pseudonetwork, targetoid\u2010like appearance and rosette sign were common dermoscopic findings of <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content> in Asians. In most cases, the treatment response correlated with the changes in dermoscopic features. These findings suggest that dermoscopy is a useful tool to monitor <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/1346-8138.12282","type":"journal-article","created":{"date-parts":[[2014,6,9]],"date-time":"2014-06-09T11:08:27Z","timestamp":1402312107000},"page":"487-493","source":"Crossref","is-referenced-by-count":28,"title":["Dermoscopic features of actinic keratosis and follow up with dermoscopy: A pilot study"],"prefix":"10.1111","volume":"41","author":[{"given":"Ji Hyun","family":"Lee","sequence":"first","affiliation":[{"name":"The Department of Dermatology Seoul St. Mary's Hospital Seoul Korea"},{"name":"St. Vincent's Hospital College of Medicine the Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chae Young","family":"Won","sequence":"additional","affiliation":[{"name":"St. Vincent's Hospital College of Medicine the Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gyong Moon","family":"Kim","sequence":"additional","affiliation":[{"name":"St. Vincent's Hospital College of Medicine the Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Si Yong","family":"Kim","sequence":"additional","affiliation":[{"name":"St. Vincent's Hospital College of Medicine the Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,11,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.103342"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.103344"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.103339"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(88)91658-3"},{"key":"e_1_2_7_6_1","first-page":"651","article-title":"Development of a treatment algorithm for actinic keratoses: a European Consensus","volume":"18","author":"Stockfleth E","year":"2008","journal-title":"Eur J Dermatol"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1978.tb06529.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000089015"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07426.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2009.86"},{"key":"e_1_2_7_11_1","first-page":"13","volume-title":"Dermoscopy: An Atlas","author":"Menzies SW","year":"2009"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.08.052"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0738-081X(02)00221-3"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.4.507"},{"key":"e_1_2_7_15_1","first-page":"270","article-title":"Dermoscopy of pigmented skin lesions","volume":"11","author":"Soyer HP","year":"2001","journal-title":"Eur J Dermatol"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.02.011"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04317.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.04.039"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.12282","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.12282","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T23:38:43Z","timestamp":1695512323000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.12282"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,8]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1111\/1346-8138.12282"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.12282","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,8]]}}}