{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T11:16:39Z","timestamp":1790507799274,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2013,12,4]],"date-time":"2013-12-04T00:00:00Z","timestamp":1386115200000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Sebaceous gland hyperplasia and increased sebum secretion after irradiation of ultraviolet (<jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>)\u2010B has been widely accepted. This study was performed to clarify expression of inflammatory cytokines after irradiating <jats:styled-content style=\"fixed-case\">UV\u2010B<\/jats:styled-content> in cultured sebocytes. Reverse transcription polymerase chain reaction was performed to measure gene expression of inflammatory cytokines, including interleukin (<jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>)\u20101\u03b2, <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20106, <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20108 and tumor necrosis factor\u2010\u03b1, in cultured sebocytes after exposure to 40 and 70\u00a0mJ\/cm<jats:sup>2<\/jats:sup> <jats:styled-content style=\"fixed-case\">UV\u2010B<\/jats:styled-content>. Protein expression of inflammatory cytokines and lipid production in cultured sebocytes after exposure to <jats:styled-content style=\"fixed-case\">UV\u2010B<\/jats:styled-content> were measured using enzyme\u2010linked immunoassay and lipid analysis kit. The expression of inflammatory cytokines, especially IL\u20101\u03b2 and IL\u20108, was significantly increased in cultured sebocytes after treatment with <jats:styled-content style=\"fixed-case\">UV\u2010B<\/jats:styled-content>. Many more studies on the effect of <jats:styled-content style=\"fixed-case\">UV\u2010B<\/jats:styled-content> on sebaceous glands should be performed to reveal the pathogenic mechanism of acne.<\/jats:p>","DOI":"10.1111\/1346-8138.12330","type":"journal-article","created":{"date-parts":[[2013,12,4]],"date-time":"2013-12-04T13:10:32Z","timestamp":1386162632000},"page":"993-997","source":"Crossref","is-referenced-by-count":31,"title":["Ultraviolet B irradiation increases the expression of inflammatory cytokines in cultured sebocytes"],"prefix":"10.1111","volume":"40","author":[{"given":"Weon Ju","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Dermatology Kyungpook National University School of Medicine Daegu Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung Hea","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kyungpook National University School of Medicine Daegu 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