{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:57:19Z","timestamp":1760245039644},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,3,17]],"date-time":"2014-03-17T00:00:00Z","timestamp":1395014400000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Langerhans cell histiocytosis (<jats:styled-content style=\"fixed-case\">LCH<\/jats:styled-content>) is a rare histiocytic neoplasm characterized by clonal proliferation of <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>angerhans cells in multi\u2010organ systems including skin, bone, pituitary gland, liver and spleen. Skin\u2010limited involvement of <jats:styled-content style=\"fixed-case\">LCH<\/jats:styled-content> usually indicates an indolent clinical course; however, in rare cases, <jats:styled-content style=\"fixed-case\">LCH<\/jats:styled-content> is accompanied by other myeloproliferative disorders, which may determine the prognosis. An 82\u2010year old Japanese man presented with numerous asymptomatic facial papules clinically simulating rhinophyma. Although findings of histopathology and general examination including bone marrow biopsy led to the diagnosis of cutaneous <jats:styled-content style=\"fixed-case\">LCH<\/jats:styled-content>, he died from chronic myelomonocytic leukemia, which emerged 10\u00a0months after the initial diagnosis of <jats:styled-content style=\"fixed-case\">LCH<\/jats:styled-content>. The previously reported cases of <jats:styled-content style=\"fixed-case\">LCH<\/jats:styled-content> concomitant with other hematological disorders are also summarized and described compared with the present case.<\/jats:p>","DOI":"10.1111\/1346-8138.12417","type":"journal-article","created":{"date-parts":[[2014,3,17]],"date-time":"2014-03-17T04:59:52Z","timestamp":1395032392000},"page":"262-265","source":"Crossref","is-referenced-by-count":12,"title":["Cutaneous <scp>L<\/scp>angerhans cell histiocytosis in elderly with chronic myelomonocytic leukemia"],"prefix":"10.1111","volume":"41","author":[{"given":"Takeshi","family":"Iwasaki","sequence":"first","affiliation":[{"name":"Dermatology Section Kitami Red Cross Hospital Kitami Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichiro","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Dermatology Section Kitami Red Cross Hospital Kitami 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