{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T22:07:54Z","timestamp":1766268474162},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,5,6]],"date-time":"2014-05-06T00:00:00Z","timestamp":1399334400000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Mycobacterium chelonae<\/jats:italic> is a non\u2010tuberculous, rapidly growing mycobacteria and is widely distributed in the natural environment. In the immunocompetent status, localized cutaneous infections such as cellulitis and subcutaneous abscesses commonly occur after traumatic injury. However, disseminated cutaneous infections occur on a background of immunosuppression. Cutaneous <jats:italic>M.\u00a0chelonae<\/jats:italic> infection presents with a variety of skin eruptions. We report a case of disseminated <jats:italic>M.\u00a0chelonae<\/jats:italic> infection mimicking cutaneous vasculitis. The patient was treated with long\u2010term oral corticosteroids and injected etanercept for the treatment of rheumatoid arthritis and asthma. Because the skin eruptions were preceded by asthma and rheumatoid arthritis and the pathological findings showed fibrinoid necrosis around the vascular of dermis, cutaneous vasculitis was first suspected. The culture from the pus revealed the bacterium which grew within 5\u00a0days on Ogawa's culture medium suggesting a rapidly growing mycobacteria. This bacterium was identified as <jats:italic>M.\u00a0chelonae<\/jats:italic> by the <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content>\u2013<jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content> hybridization method. We chose 800\u00a0mg\/day clarithromycin and 500\u00a0mg\/day levofloxacin as a result of the drug\u2010sensitivity test. After 6\u00a0months of the treatment, infection symptoms disappeared. Rapidly growing mycobacteria should be considered in the differential diagnosis of infections in patients under immunosuppression caused by diseases or drugs such as corticosteroids and biologic agents. Repeated bacterial examinations are important and required for the diagnosis of rapidly growing mycobacteria.<\/jats:p>","DOI":"10.1111\/1346-8138.12459","type":"journal-article","created":{"date-parts":[[2014,5,7]],"date-time":"2014-05-07T02:42:25Z","timestamp":1399430545000},"page":"414-417","source":"Crossref","is-referenced-by-count":19,"title":["Case of disseminated cutaneous <i><scp>M<\/scp>ycobacterium chelonae<\/i> infection mimicking cutaneous vasculitis"],"prefix":"10.1111","volume":"41","author":[{"given":"Asako","family":"Ichihara","sequence":"first","affiliation":[{"name":"Department of Dermatology and Plastic Surgery Faculty of Life Sciences Kumamoto University Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masatoshi","family":"Jinnin","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Plastic Surgery Faculty of Life Sciences Kumamoto University Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Fukushima","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Plastic Surgery Faculty of Life Sciences Kumamoto University Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Plastic Surgery Faculty of Life Sciences Kumamoto University Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hironobu","family":"Ihn","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Plastic Surgery Faculty of Life Sciences Kumamoto University Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,5,6]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(16)34193-1"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2012.06.029"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.03.034"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-012-1766-8"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eimc.2011.05.008"},{"key":"e_1_2_5_7_1","first-page":"515","article-title":"Disseminated cutaneous infection with Mycobacterium chelonae mimicking panniculitis in a patient with dermatomyositis","volume":"11","author":"Leung YY","year":"2005","journal-title":"Hong Kong Med J"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3182120ae3"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2012.08.002"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.179.3.1872"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4614-6111-1_7"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2010.03.011"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.168.9.4620"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2009.09.008"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.05399-11"},{"key":"e_1_2_5_16_1","first-page":"101","article-title":"Mycobacterium chelonae infection under adalimumab therapy for spondylarthritis","volume":"28","author":"Kluger N","year":"2010","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-119-6-199309150-00006"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(97)80242-3"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1053\/jinf.2001.0880"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2011.01246.x"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.12459","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.12459","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T10:07:46Z","timestamp":1695550066000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.12459"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["10.1111\/1346-8138.12459"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.12459","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5]]}}}