{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T09:37:39Z","timestamp":1778837859361,"version":"3.51.4"},"reference-count":13,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,4,19]],"date-time":"2014-04-19T00:00:00Z","timestamp":1397865600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Entero\u2010Beh\u00e7et's disease coexisting with long\u2010term epilepsy and schizophrenia\u2010like symptoms is presented. A 43\u2010year\u2010old woman presented with repeatedly occurring aphthous stomatitis for several years. She had been treated for absence seizures, epilepsy and schizophrenia since she was 9\u00a0years old. She presented with multiple aphthous stomatitis on her gingiva, erythema nodosum\u2010like symptoms on the right lateral aspect of her leg and genital ulcers on her perianal area. She also showed polyarthritis. Laboratory examinations revealed elevated C\u2010reactive protein, elevated neutrophil counts, decreased serum Fe and elevated serum Cu. Histological examination showed perivascular neutrophil and mononuclear cell infiltrates and eosinophilic change of the vessel wall in the lobules of subcutaneous fat tissue. Six weeks after the oral prednisolone therapy, she showed resolution of aphthous stomatitis, folliculitis\u2010like eruption and genital ulcer. She experienced severe abdominal pain after the start of treatment of Beh\u00e7et's disease. Plain computed tomography revealed edematous change in the appendix, and ascending and transverse colon. These results led to the diagnosis of entero\u2010Beh\u00e7et's disease acute exaggeration. Treatment with infliximab (300\u00a0mg\/once) was started. Eight weeks after the start of infliximab, her abdominal pain disappeared and C\u2010reactive protein decreased, followed by the successful change to adalimumab infusion therapy.<\/jats:p>","DOI":"10.1111\/1346-8138.12470","type":"journal-article","created":{"date-parts":[[2014,4,19]],"date-time":"2014-04-19T11:20:01Z","timestamp":1397906401000},"page":"424-426","source":"Crossref","is-referenced-by-count":2,"title":["Entero\u2010Beh\u00e7et's disease coexisting with long\u2010term epilepsy and schizophrenia\u2010like symptoms"],"prefix":"10.1111","volume":"41","author":[{"given":"Tsutomu","family":"Ohtsuka","sequence":"first","affiliation":[{"name":"Department of Dermatology International University of Health and Welfare Hospital Nasushiobara Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,19]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2004.02.008"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.2002.01102.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-006-0016-4"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.bor.0000197995.27579.9b"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.23345"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2006.01613.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.genhosppsych.2012.06.007"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1586\/ern.09.11"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2011.08.014"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-011-1726-1"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000342738"},{"key":"e_1_2_5_13_1","first-page":"60","article-title":"Update on idiopathic colitides","volume":"29","author":"Strobel S","year":"2013","journal-title":"Curr Opin Gastroenterol"},{"key":"e_1_2_5_14_1","unstructured":"OzawaM.A study of Adalimumab in Japanese Subjects with Intestinal Behcet disease.www.ClinicalTrials.gov."}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.12470","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.12470","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T10:07:20Z","timestamp":1695550040000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.12470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,19]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["10.1111\/1346-8138.12470"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.12470","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,19]]}}}