{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T12:10:06Z","timestamp":1754395806389},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,5,10]],"date-time":"2014-05-10T00:00:00Z","timestamp":1399680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a case of an 88\u2010year\u2010old woman with a decalvant, erythematous, ulcerated tumor extending from the right temporal to occipital region. Histopathological analysis revealed a dense infiltration of medium\u2010to\u2010large\u2010sized atypical cells throughout the entire dermis. The result of immunohistochemical analysis showed that the infiltrating T cells expressed programmed death\u20101 (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>\u20101), <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>cl\u20106 and <jats:styled-content style=\"fixed-case\">CXCL<\/jats:styled-content>13. Flow cytometry analysis showed that <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>4<jats:sup>+<\/jats:sup> <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>\u20101<jats:sup>hi<\/jats:sup> T cells also expressed <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>10, inducible T\u2010cell co\u2010stimulator and <jats:styled-content style=\"fixed-case\">CXCR<\/jats:styled-content>5. On the basis of the clinical appearance and the histopathological findings, we diagnosed the patient with primary cutaneous peripheral T\u2010cell lymphoma, not otherwise specified. Recently, the concept of primary cutaneous follicular helper T (<jats:styled-content style=\"fixed-case\">TFH<\/jats:styled-content>)\u2010cell lymphoma was proposed, and in this case, tumor cells clearly expressed <jats:styled-content style=\"fixed-case\">TFH<\/jats:styled-content>\u2010cell markers. Therefore, we considered this case to be a variant of the entity. Although this entity is still provisional, this case supports the new concept.<\/jats:p>","DOI":"10.1111\/1346-8138.12493","type":"journal-article","created":{"date-parts":[[2014,5,10]],"date-time":"2014-05-10T07:52:41Z","timestamp":1399708361000},"page":"529-532","source":"Crossref","is-referenced-by-count":10,"title":["Case of primary cutaneous peripheral T\u2010cell lymphoma, not otherwise specified, with characteristics of follicular helper T cells"],"prefix":"10.1111","volume":"41","author":[{"given":"Machiko","family":"Takaki","sequence":"first","affiliation":[{"name":"Department of Dermatology University of Yamanashi Chuo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Inozume","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Yamanashi Chuo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takamitsu","family":"Matsuzawa","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Yamanashi Chuo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriko","family":"Ando","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Yamanashi Chuo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miyuki","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Yamanashi Chuo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazutoshi","family":"Harada","sequence":"additional","affiliation":[{"name":"Department of Dermatology Tokyo Medical University Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuyoshi","family":"Kawamura","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Yamanashi Chuo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naotaka","family":"Shibagaki","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Yamanashi Chuo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Shimada","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Yamanashi Chuo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,5,10]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2011.3269"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1626"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12204"},{"key":"e_1_2_5_5_1","article-title":"Expression of follicular helper T\u2010cell markers in primary cutaneous T\u2010cell lymphoma","author":"Park JH","year":"2013","journal-title":"Am J Dermatopathol"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2010.03498.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2012.1545"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2012.124"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31818e52fe"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318230df87"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31817f123e"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.12493","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.12493","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T23:39:30Z","timestamp":1695512370000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.12493"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,10]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1111\/1346-8138.12493"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.12493","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,10]]}}}