{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T06:03:57Z","timestamp":1757311437345},"reference-count":15,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,5,10]],"date-time":"2014-05-10T00:00:00Z","timestamp":1399680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The objective of this study was to demonstrate the clinical profiles of Stevens\u2013Johnson syndrome (<jats:styled-content style=\"fixed-case\">SJS<\/jats:styled-content>) in Thai patients, and to compare those clinical features between younger and older patients. Medical records of all patients with <jats:styled-content style=\"fixed-case\">SJS<\/jats:styled-content> who were admitted to Srinagarind Hospital Medical School, Khon Kaen, Thailand, from January 2002 to December 2014 were reviewed. Epidemiological features, etiologies, treatment and clinical outcomes were collected. There were 45 patients with <jats:styled-content style=\"fixed-case\">SJS<\/jats:styled-content> during the 10\u2010year period. Females were the majority (57.8%) and the median age was 49\u00a0years. Hepatitis was the most frequent complication (67.5%). Phenytoin (15.6%), sulfonamide drugs (15.6%) and allopurinol (13.3%) were implicated as leading causes of <jats:styled-content style=\"fixed-case\">SJS<\/jats:styled-content>. Steroids were prescribed in 37 cases (82.2%). The mortality rate was 4.4%. Comparing older patients to younger patients, allopurinol appeared to be the main instigating drug to develop <jats:styled-content style=\"fixed-case\">SJS<\/jats:styled-content> with an odds ratio of 5.6 (95% confidence interval, 2.8\u201310.6). In conclusion, clinical features of Thai patients with <jats:styled-content style=\"fixed-case\">SJS<\/jats:styled-content> were similar to other reports. Allopurinol had the strongest association with <jats:styled-content style=\"fixed-case\">SJS<\/jats:styled-content> in older patients as compared to the younger ones.<\/jats:p>","DOI":"10.1111\/1346-8138.12499","type":"journal-article","created":{"date-parts":[[2014,5,10]],"date-time":"2014-05-10T07:53:11Z","timestamp":1399708391000},"page":"634-637","source":"Crossref","is-referenced-by-count":5,"title":["Clinical profiles of Stevens\u2013Johnson syndrome among Thai patients"],"prefix":"10.1111","volume":"41","author":[{"given":"Panita","family":"Limpawattana","sequence":"first","affiliation":[{"name":"Division of Geriatric Medicine Department of Medicine Faculty of Medicine Khon Kaen University Khon Kaen Thailand"},{"name":"Integrated Epilepsy Research Group Khon Kaen University Khon Kaen Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charoen","family":"Choonhakarn","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Medicine Faculty of Medicine Khon Kaen University Khon Kaen Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kannikar","family":"Kongbunkiat","sequence":"additional","affiliation":[{"name":"Division of Neurology Department of Medicine Faculty of Medicine Khon Kaen University Khon Kaen Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,5,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.2332\/allergolint.55.9"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1169"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cger.2007.01.002"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.16782"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2332\/allergolint.O-07-483"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.08.036"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.4076\/1757-1626-2-7748"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2010.02533.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0b013e328330a3b8"},{"key":"e_1_2_7_11_1","first-page":"216","article-title":"European Dermatology Forum: skin diseases in Europe. 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