{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T11:43:36Z","timestamp":1695555816085},"reference-count":16,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,9,16]],"date-time":"2014-09-16T00:00:00Z","timestamp":1410825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"JSPS KAKENHI","award":["26860882"],"award-info":[{"award-number":["26860882"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hereditary angioedema (<jats:styled-content style=\"fixed-case\">HAE<\/jats:styled-content>) presents as severe angioedema, which is mostly due to the <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>1 inhibitor (<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>1\u2010<jats:styled-content style=\"fixed-case\">INH<\/jats:styled-content>) gene mutations. Environmental factors, minor trauma and oral contraceptives have been reported to induce angioedema attack, but the trigger may often be uncertain. Activated factor <jats:styled-content style=\"fixed-case\">XII<\/jats:styled-content> controlled by <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>1\u2010<jats:styled-content style=\"fixed-case\">INH<\/jats:styled-content> facilitates bradykinin generation and also regulates coagulation cascade, but the relationship between edema formation and coagulation is still unclear. We have described a 35\u2010year\u2010old female patient with <jats:styled-content style=\"fixed-case\">HAE<\/jats:styled-content>, presenting with frequent angioedema attacks in the absence of an apparent triggering factor. She showed higher levels of <jats:styled-content style=\"fixed-case\">FDP<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>\u2010dimer during angioedema than those in remission. In addition, tissue factor (<jats:styled-content style=\"fixed-case\">TF<\/jats:styled-content>), an initiator of the extrinsic coagulation cascade, was expressed on the surface of monocytes. It was significantly higher than that of monocytes from healthy controls and tends to further increase during attacks. The expression of <jats:styled-content style=\"fixed-case\">TF<\/jats:styled-content> on monocytes may play a role in the induction of angioedema attacks in <jats:styled-content style=\"fixed-case\">HAE<\/jats:styled-content> by activating the coagulation pathway in association with reduced functions of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>1\u2010<jats:styled-content style=\"fixed-case\">INH<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/1346-8138.12610","type":"journal-article","created":{"date-parts":[[2014,9,16]],"date-time":"2014-09-16T12:41:37Z","timestamp":1410871297000},"page":"929-932","source":"Crossref","is-referenced-by-count":4,"title":["Tissue factor expression on the surface of monocytes from a patient with hereditary angioedema"],"prefix":"10.1111","volume":"41","author":[{"given":"Kazumasa","family":"Iwamoto","sequence":"first","affiliation":[{"name":"Department of Dermatology Integrated Health Sciences Institute of Biomedical and Health Sciences Hiroshima University Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Morioke","sequence":"additional","affiliation":[{"name":"Department of Dermatology Integrated Health Sciences Institute of Biomedical and Health Sciences Hiroshima University Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhki","family":"Yanase","sequence":"additional","affiliation":[{"name":"Department of Dermatology Integrated Health Sciences Institute of Biomedical and Health Sciences Hiroshima University Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazue","family":"Uchida","sequence":"additional","affiliation":[{"name":"Department of Dermatology Integrated Health Sciences Institute of Biomedical and Health Sciences Hiroshima University Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michihiro","family":"Hide","sequence":"additional","affiliation":[{"name":"Department of Dermatology Integrated Health Sciences Institute of Biomedical and Health Sciences Hiroshima University Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,16]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199207000-00003"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1710-1492-6-24"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.2165\/11599490-000000000-00000"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2008.01859.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.08.012"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2009.02234.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V89.9.3213"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2011.04138.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2009.02222.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH09-01-0023"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2011.11.049"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1614888"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.08.043"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000155748"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/cei.12098"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.8.4962"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.12610","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.12610","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T11:02:40Z","timestamp":1695553360000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.12610"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,16]]},"references-count":16,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["10.1111\/1346-8138.12610"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.12610","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,16]]}}}