{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T12:59:25Z","timestamp":1753275565815},"reference-count":11,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2014,10,9]],"date-time":"2014-10-09T00:00:00Z","timestamp":1412812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Cancer Center Research and Development Fund","award":["26-A-4"],"award-info":[{"award-number":["26-A-4"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Basal cell carcinoma (<jats:styled-content style=\"fixed-case\">BCC<\/jats:styled-content>) is a common malignant skin tumor. However, <jats:styled-content style=\"fixed-case\">BCC<\/jats:styled-content> that arise at the umbilicus is rare. We present three cases of umbilical <jats:styled-content style=\"fixed-case\">BCC<\/jats:styled-content>. Each <jats:styled-content style=\"fixed-case\">BCC<\/jats:styled-content> was excised at a different depth level, and all deep surgical margins were negative. All patients had no evidence of local recurrence or metastasis during the follow\u2010up periods (12, 24, and 52\u00a0months). Reviewing the reported cases of umbilical <jats:styled-content style=\"fixed-case\">BCC<\/jats:styled-content>, the <jats:styled-content style=\"fixed-case\">BCC<\/jats:styled-content> cells did not seem to invade into the umbilical scar in most cases, and the deepest invasion levels of tumor cells were up to the middle layer of the subcutaneous tissue. However, the dermatological surgeons have to consider the possibility of surgical excision down to and including the umbilical attachment to the peritoneum, and intraoperative margin assessment should be necessary to avoid the risk of excessive or incomplete excision.<\/jats:p>","DOI":"10.1111\/1346-8138.12640","type":"journal-article","created":{"date-parts":[[2014,10,9]],"date-time":"2014-10-09T06:57:45Z","timestamp":1412837865000},"page":"992-995","source":"Crossref","is-referenced-by-count":9,"title":["Surgical management of umbilical basal cell carcinoma: Published work review and the optimal depth of surgical excision"],"prefix":"10.1111","volume":"41","author":[{"given":"Yasuhiro","family":"Nakamura","sequence":"first","affiliation":[{"name":"Department of Skin Oncology\/Dermatology Saitama Medical University International Medical Center Hidaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukiko","family":"Teramoto","sequence":"additional","affiliation":[{"name":"Department of Skin Oncology\/Dermatology Saitama Medical University International Medical Center Hidaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryota","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine University of Tsukuba Tsukuba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiyuki","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine University of Tsukuba Tsukuba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Maruyama","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine University of Tsukuba Tsukuba 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