{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:22:58Z","timestamp":1787962978101,"version":"build-2784847793"},"reference-count":10,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2014,10,25]],"date-time":"2014-10-25T00:00:00Z","timestamp":1414195200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Pemphigus is a group of autoimmune blistering diseases that affect the skin and mucous membranes. A reliable and accurate disease severity tool to assess pemphigus severity is crucial for managing pemphigus and for clinical trials. The purpose of this study was to compare the pemphigus disease area index activity score (<jats:styled-content style=\"fixed-case\">PDAI<\/jats:styled-content>), the Japanese pemphigus disease severity score (<jats:styled-content style=\"fixed-case\">JPDSS<\/jats:styled-content>) and the physician's subjective impression, and also to find appropriate severity grading cut\u2010offs for the <jats:styled-content style=\"fixed-case\">PDAI<\/jats:styled-content>. We also evaluated the correlation between <jats:styled-content style=\"fixed-case\">PDAI<\/jats:styled-content> activity score and the <jats:styled-content style=\"fixed-case\">JPDSS<\/jats:styled-content>. Thirty\u2010seven pemphigus patients and 110 assessments were analyzed in this study. The optimal points of pemphigus disease severity score in <jats:styled-content style=\"fixed-case\">PDAI<\/jats:styled-content> were: mild (0\u20138), moderate (9\u201324) and severe (\u226525). In mild or moderate cases, the <jats:styled-content style=\"fixed-case\">JPDSS<\/jats:styled-content> was well correlated with the <jats:styled-content style=\"fixed-case\">PDAI<\/jats:styled-content>, but in severe cases the <jats:styled-content style=\"fixed-case\">JPDSS<\/jats:styled-content> reached a plateau at a <jats:styled-content style=\"fixed-case\">PDAI<\/jats:styled-content> score of approximately 30. The <jats:styled-content style=\"fixed-case\">PDAI<\/jats:styled-content> evaluates disease severity more accurately than the <jats:styled-content style=\"fixed-case\">JPDSS<\/jats:styled-content>, particularly in severe cases. The <jats:styled-content style=\"fixed-case\">PDAI<\/jats:styled-content> is not only a useful tool to measure the extent of cutaneous lesions, but also an excellent scoring system for evaluating pemphigus disease severity.<\/jats:p>","DOI":"10.1111\/1346-8138.12649","type":"journal-article","created":{"date-parts":[[2014,10,31]],"date-time":"2014-10-31T10:12:24Z","timestamp":1414750344000},"page":"969-973","source":"Crossref","is-referenced-by-count":65,"title":["Grading criteria for disease severity by pemphigus disease area index"],"prefix":"10.1111","volume":"41","author":[{"given":"Tomoko","family":"Shimizu","sequence":"first","affiliation":[{"name":"Department of Dermatology Keio University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Takebayashi","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Public Health Keio University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Center for Clinical Research Keio University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hironori","family":"Niizeki","sequence":"additional","affiliation":[{"name":"Department of Dermatology National Center for Child Health and Development Tokyo Japan"},{"name":"Nara Medical University School of Medicine Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumi","family":"Aoyama","sequence":"additional","affiliation":[{"name":"Okayama University Hospital Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo","family":"Kitajima","sequence":"additional","affiliation":[{"name":"Kizawa Memorial Hospital Gifu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiji","family":"Iwatsuki","sequence":"additional","affiliation":[{"name":"Okayama University Hospital Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"Kurume University School of Medicine Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Yamagami","sequence":"additional","affiliation":[{"name":"Department of Dermatology Keio University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria P.","family":"Werth","sequence":"additional","affiliation":[{"name":"Philadelphia V.A. Medical Center Philadelphia Pennsylvania USA"},{"name":"University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Amagai","sequence":"additional","affiliation":[{"name":"Department of Dermatology Keio University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiko","family":"Tanikawa","sequence":"additional","affiliation":[{"name":"Department of Dermatology Keio University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.01.012"},{"key":"e_1_2_7_3_1","first-page":"183","volume-title":"Annual Report of the Intractable Skin Diseases Study Group (in Japanese)","author":"Ogawa H","year":"1994"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.09.052"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-002-0367-2"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2009.72"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/bimj.200410133"},{"key":"e_1_2_7_8_1","first-page":"4","article-title":"Introducing a novel Autoimmune Bullous Skin Disorder Intensity Score (ABSIS) in pemphigus","volume":"17","author":"Pf\u00fctze M","year":"2007","journal-title":"Eur J Dermatol"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2011.03.017"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2013.8175"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2008.02715.x"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.12649","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.12649","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T21:28:38Z","timestamp":1695504518000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.12649"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,25]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.1111\/1346-8138.12649"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.12649","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,25]]}}}