{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T03:44:08Z","timestamp":1792381448650,"version":"4.4.0"},"reference-count":14,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,10,30]],"date-time":"2014-10-30T00:00:00Z","timestamp":1414627200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Congenital self\u2010healing Langerhans cell histiocytosis or Hashimoto\u2010Pritzker disease is a rare condition present at birth or in the neonatal period characterized by small reddish\u2010brown crusted papulonodular lesions. In most cases these lesions are not accompanied by systemic findings and tend to involute spontaneously within weeks or months, but in other cases there may be extracutaneous involvement and\/or recurrence of the disease. This emphasizes that the clinical course is variable and a long\u2010term follow\u2010up is mandatory in order to reveal possible systemic involvement. We describe two cases of congenital self\u2010healing Langerhans cell histiocytosis with widespread and very similar cutaneous manifestations but different clinical course. The first patient had multisystemic disease (with lymph nodes, bones, liver and lungs affected) that required systemic therapy. The second patient had cutaneous and bony lesions that resolved spontaneously. We think that the adjective \u201cself\u2010healing\u201d is misleading and should be abandoned. We stress the importance of a complete systemic evaluation and the necessity of a long\u2010term follow\u2010up.<\/jats:p>","DOI":"10.1111\/1346-8138.12670","type":"journal-article","created":{"date-parts":[[2014,10,30]],"date-time":"2014-10-30T06:57:08Z","timestamp":1414652228000},"page":"1098-1101","source":"Crossref","is-referenced-by-count":21,"title":["Congenital \u201cself\u2010healing\u201d <scp>L<\/scp>angerhans cell histiocytosis (<scp>H<\/scp>ashimoto\u2010<scp>P<\/scp>ritzker disease): A report of two cases with the same cutaneous manifestations but different clinical course"],"prefix":"10.1111","volume":"41","author":[{"given":"Victor Desmond","family":"Mandel","sequence":"first","affiliation":[{"name":"Department of Dermatology University of Modena and Reggio Emilia Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Modena and Reggio Emilia Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Maria","family":"Cesinaro","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology University of Modena and Reggio Emilia Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Pellacani","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Modena and Reggio Emilia Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corrado","family":"Del Forno","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Modena and Reggio Emilia Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,30]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1973.01620170071020"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199104000-00014"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1986.tb00519.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1986.tb00867.x"},{"issue":"10","key":"e_1_2_6_6_1","doi-asserted-by":"crossref","first-page":"2","DOI":"10.5070\/D378V7Z5W4","article-title":"Congenital self\u2010healing reticulohistiocytosis: concern for a poor prognosis","volume":"18","author":"Larsen L","year":"2012","journal-title":"Dermatol Online J"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.09.001"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2009.360"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(93)90133-2"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0463.2003.1110202.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.155.7.778"},{"key":"e_1_2_6_12_1","first-page":"208","article-title":"Histiocytosis syndromes in children","volume":"329","author":"The Writing Group of the Histiocyte Society","year":"1987","journal-title":"Lancet"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(94)70258-6"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(85)70192-2"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0344-0338(11)80007-5"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.12670","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.12670","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T17:09:12Z","timestamp":1695575352000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.12670"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,30]]},"references-count":14,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["10.1111\/1346-8138.12670"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.12670","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,30]]}}}