{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T16:52:52Z","timestamp":1770483172131,"version":"3.49.0"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,12,6]],"date-time":"2014-12-06T00:00:00Z","timestamp":1417824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Granulomatous cheilitis (<jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content>) is an uncommon disease and the pathogenesis of <jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content> has not been clear. Here, we present two cases of <jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content> associated with calcium deposition caused by chronic inflammation owing to dental metal allergy and periodontitis. Histopathologically, intralymphatic histiocytosis (<jats:styled-content style=\"fixed-case\">IH<\/jats:styled-content>) in addition to non\u2010caseating granulomas was seen in both cases. The results of a patch test were positive for some dental metals. Qualitative analyses by energy\u2010dispersive X\u2010ray spectroscopy detected calcium from biopsy specimens. We considered that partial destruction of teeth by chronic inflammation induced reactive proliferation of histiocytes, resulting in <jats:styled-content style=\"fixed-case\">IH<\/jats:styled-content>. Our study suggests that <jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">IH<\/jats:styled-content> is a consequence of chronic inflammatory diseases caused by dental metals and periodontitis. Dental care is necessary for treatment of <jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/1346-8138.12713","type":"journal-article","created":{"date-parts":[[2014,12,9]],"date-time":"2014-12-09T04:17:41Z","timestamp":1418098661000},"page":"84-86","source":"Crossref","is-referenced-by-count":10,"title":["Granulomatous cheilitis with intralymphatic histiocytosis possibly associated with calcium deposition caused by chronic inflammation owing to dental metals and periodontitis"],"prefix":"10.1111","volume":"42","author":[{"given":"Shinya","family":"Kano","sequence":"first","affiliation":[{"name":"Division of Dermatology Department of Medicine of Sensory and Motor Organs Faculty of Medicine Tottori University Yonago Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shingo","family":"Kurimoto","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Medicine of Sensory and Motor Organs Faculty of Medicine Tottori University Yonago Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayako","family":"Ito","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Medicine of Sensory and Motor Organs Faculty of Medicine Tottori University Yonago Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Medicine of Sensory and Motor Organs Faculty of Medicine Tottori University Yonago Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Medicine of Sensory and Motor Organs Faculty of Medicine Tottori University Yonago Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,12,6]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-013-0488-2"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1994.tb00519.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3181f04912"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2008.01500.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2003.00793.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(03)02185-6"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1990.tb02123.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3181986cc2"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.08295.x"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.12713","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.12713","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T00:23:49Z","timestamp":1694651029000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.12713"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,6]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1111\/1346-8138.12713"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.12713","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,6]]}}}