{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T02:14:26Z","timestamp":1780539266386,"version":"3.54.1"},"reference-count":7,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T00:00:00Z","timestamp":1418688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2015,2]]},"abstract":"Abstract<\/jats:title>We report a case of Merkel cell carcinoma (MCC<\/jats:styled-content>) on the dorsal aspect of the right middle finger associated with multiple squamous cell carcinomas (SCC<\/jats:styled-content>) possibly arising in chronic radiation dermatitis of the hand of an 80\u2010year\u2010old surgeon. In spite of resection of the primary lesion and right axillary lymph nodes, he died of the tumor 5\u00a0months after the first visit. Cutaneous and lymph node lesions of MCC<\/jats:styled-content> were negative for Merkel cell polyoma virus (MCPyV<\/jats:styled-content>) by immunostaining using monoclonal antibody (CM<\/jats:styled-content>2B4) and anti\u2010large T antigen of MCPyV<\/jats:styled-content> polyclonal antibody, and real\u2010time polymerase chain reaction. Several differences in clinicopathological findings have been found between MCPyV<\/jats:styled-content>\u2010positive cases and negative ones. Several authors have reported that MCPyV<\/jats:styled-content>\u2010negative cases have a worse prognosis than MCPyV<\/jats:styled-content>\u2010positive ones. Furthermore, in cases of MCC<\/jats:styled-content> associated with SCC<\/jats:styled-content>, most tumors have been reported to be MCPyV<\/jats:styled-content>\u2010negative. We should pay more attention to the relationship between the carcinogenesis of MCC<\/jats:styled-content> and ionizing irradiation.<\/jats:p>","DOI":"10.1111\/1346-8138.12737","type":"journal-article","created":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T10:12:47Z","timestamp":1418724767000},"page":"207-209","source":"Crossref","is-referenced-by-count":14,"title":["Case of Merkel cell carcinoma with squamous cell carcinoma possibly arising in chronic radiodermatitis of the hand"],"prefix":"10.1111","volume":"42","author":[{"given":"Shin\u2010ichi","family":"Ansai","sequence":"first","affiliation":[{"name":"Division of Dermatology Nippon Medical School Musashi Kosugi Hospital Kawasaki Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachiko","family":"Noro","sequence":"additional","affiliation":[{"name":"Department of Dermatology Nippon Medical School Musashi Kosugi Hospital Kawasaki Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azusa","family":"Ogita","sequence":"additional","affiliation":[{"name":"Division of Dermatology Nippon Medical School Musashi Kosugi Hospital Kawasaki Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitomi","family":"Fukumoto","sequence":"additional","affiliation":[{"name":"Department of Dermatology Nippon Medical School Musashi Kosugi Hospital Kawasaki Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harutaka","family":"Katano","sequence":"additional","affiliation":[{"name":"Department of Pathology National Institute of Infectious Diseases Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiji","family":"Kawana","sequence":"additional","affiliation":[{"name":"Department of Dermatology Nippon Medical School Musashi Kosugi Hospital Kawasaki Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,12,16]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2011.01.020"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1152586"},{"key":"e_1_2_5_4_1","first-page":"464","article-title":"Post\u2010radiotherapy cutaneous neuro\u2010endocrine carcinoma","volume":"123","author":"Lardy F","year":"1996","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2012.10.598"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djp139"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25136"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1001076"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.12737","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.12737","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T06:57:38Z","timestamp":1695538658000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.12737"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,16]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["10.1111\/1346-8138.12737"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.12737","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,16]]}}}