{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T13:15:04Z","timestamp":1789823704019,"version":"4.0.1"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,1,13]],"date-time":"2015-01-13T00:00:00Z","timestamp":1421107200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2015,3]]},"abstract":"Abstract<\/jats:title>\n \n This study was designed to investigate the relationship between plasma lipid profile and acne. Acne patients (\n n<\/jats:italic>\n \u00a0=\u00a0181) and healthy volunteers (\n n<\/jats:italic>\n \u00a0=\u00a0130) matched in terms of both age and sex were enrolled. Plasma total cholesterol (\n TC<\/jats:styled-content>\n ), triglyceride (\n TG<\/jats:styled-content>\n ), high\u2010density lipoprotein cholesterol, low\u2010density lipoprotein cholesterol (\n LDL<\/jats:styled-content>\n \u2010C) and lipoprotein (\n LP<\/jats:styled-content>\n )(a) levels were measured.\n TC<\/jats:styled-content>\n ,\n LDL<\/jats:styled-content>\n \u2010C and\n LP<\/jats:styled-content>\n (a) levels in male and female patients with severe acne were significantly higher than in the healthy control group (\n P\u00a0<\/jats:italic>\n <\n \u00a0<\/jats:italic>\n 0.05).\n TG<\/jats:styled-content>\n in male patients with severe and moderate acne was significantly higher than in the healthy control group (\n P<\/jats:italic>\n \u00a0<\u00a00.05).\n LP<\/jats:styled-content>\n (a) in male and female patients with mild, moderate and severe acne was significantly higher than in the healthy control group (\n P<\/jats:italic>\n \u00a0<\u00a00.05). The constituent ratio of male and female patients with\n TC<\/jats:styled-content>\n ,\n TG<\/jats:styled-content>\n ,\n LDL<\/jats:styled-content>\n \u2010C and\n LP<\/jats:styled-content>\n (a) over the normal range was signi\u2010ficantly higher than in the healthy control group. In this study, acne patients were frequently associated with abnormal lipid profile, providing a new basis for further exploration of the pathogenesis, as well as new treatments, of acne vulgaris.\n <\/jats:p>","DOI":"10.1111\/1346-8138.12761","type":"journal-article","created":{"date-parts":[[2015,1,13]],"date-time":"2015-01-13T15:13:38Z","timestamp":1421162018000},"page":"296-299","source":"Crossref","is-referenced-by-count":34,"title":["Acne patients frequently associated with abnormal plasma lipid profile"],"prefix":"10.1111","volume":"42","author":[{"given":"Hao","family":"Jiang","sequence":"first","affiliation":[{"name":"Dermatological Department Clinical Laboratory Medical Center and Research Department of The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang Yi","family":"Li","sequence":"additional","affiliation":[{"name":"Dermatological Department Clinical Laboratory Medical Center and Research Department of The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Zhou","sequence":"additional","affiliation":[{"name":"Dermatological Department Clinical Laboratory Medical Center and Research Department of The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Lu","sequence":"additional","affiliation":[{"name":"Dermatological Department Clinical Laboratory Medical Center and Research Department of The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinghui","family":"Lin","sequence":"additional","affiliation":[{"name":"Dermatological Department Clinical Laboratory Medical Center and Research Department of The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqi","family":"Huang","sequence":"additional","affiliation":[{"name":"Dermatological Department Clinical Laboratory Medical Center and Research Department of The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Wei","sequence":"additional","affiliation":[{"name":"Ruikang Hospital Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Wang","sequence":"additional","affiliation":[{"name":"Ruikang Hospital Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leping","family":"Wang","sequence":"additional","affiliation":[{"name":"Dongzhimen Hospital of Beijing University of Chinese Medicine Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianqi","family":"Lu","sequence":"additional","affiliation":[{"name":"Dermatological Department Clinical Laboratory Medical Center and Research Department of The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/858176"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1248\/jhs.53.596"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2009000600005"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2007.00403.x-i1"},{"key":"e_1_2_6_6_1","first-page":"390","article-title":"Chinese guidelines on prevention and treatment of dyslipidemia in adults","volume":"35","author":"Joint Committee for Developing Chinese 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