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Because it contains fibrin and high concentrations of growth factors, PRP is known to promote wound healing. In this study, we present five patients with chronic foot ulcers successfully treated with <jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> in our institution. The patients had various underlying diseases: diabetes (<jats:italic>n\u00a0<\/jats:italic>=\u00a02), peripheral arterial disease (<jats:italic>n\u00a0<\/jats:italic>=\u00a01), both diabetes and <jats:styled-content style=\"fixed-case\">peripheral arterial disease (<jats:italic>n\u00a0<\/jats:italic>=\u00a01)<\/jats:styled-content>, and cutaneous polyarteritis nodosa (<jats:italic>n\u00a0<\/jats:italic>=\u00a01). Also, we provide a description of <jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content>'s mechanisms, advantages, and limitations.<\/jats:p>","DOI":"10.1111\/1346-8138.12777","type":"journal-article","created":{"date-parts":[[2015,1,23]],"date-time":"2015-01-23T11:06:37Z","timestamp":1422011197000},"page":"288-295","source":"Crossref","is-referenced-by-count":17,"title":["Case series of patients with chronic foot ulcers treated with autologous platelet\u2010rich plasma"],"prefix":"10.1111","volume":"42","author":[{"given":"Rie R.","family":"Yotsu","sequence":"first","affiliation":[{"name":"Department of Dermatology National Center for Global Health and Medicine Tokyo Japan"},{"name":"Department of Dermatology National Suruga Sanatorium Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shotaro","family":"Hagiwara","sequence":"additional","affiliation":[{"name":"Department of Hematology National Center for Global Health and Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Okochi","sequence":"additional","affiliation":[{"name":"Department of Dermatology National Center for Global Health and Medicine Tokyo Japan"},{"name":"Department of Regenerative Medicine National Center for Global Health and Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Tamaki","sequence":"additional","affiliation":[{"name":"Department of Dermatology National Center for Global Health and Medicine Tokyo 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