{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:10:28Z","timestamp":1789603828116,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,3,26]],"date-time":"2015-03-26T00:00:00Z","timestamp":1427328000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Circulating inflammatory cytokines and markers are increased in patients with psoriasis. Recent studies have shown that a higher red blood cell distribution width (\n                    <jats:styled-content style=\"fixed-case\">RDW<\/jats:styled-content>\n                    ) is associated with disease activity in various disorders. Our objective was to investigate whether\n                    <jats:styled-content style=\"fixed-case\">RDW<\/jats:styled-content>\n                    is increased in psoriasis patients, and to evaluate its possible association with disease severity. We conducted a retrospective study of psoriasis patients seen in a university hospital in South Korea. Information about demographics, hematological parameters and disease severity were collected. Statistical analysis was performed using Student's\n                    <jats:italic>t<\/jats:italic>\n                    \u2010test, multivariable logistic regression, Fisher's exact test and Spearman's rank correlation coefficient analysis as appropriate. A total of 261 psoriasis patients and 102 healthy controls were included in our study. The mean\n                    <jats:styled-content style=\"fixed-case\">RDW<\/jats:styled-content>\n                    value was significantly increased in psoriasis patients compared with healthy control (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.037). Compared with mild psoriasis patients (Psoriasis Area and Severity Index [\n                    <jats:styled-content style=\"fixed-case\">PASI<\/jats:styled-content>\n                    ], &lt;7), moderate to severe patients (\n                    <jats:styled-content style=\"fixed-case\">PASI<\/jats:styled-content>\n                    , \u22657) showed significantly higher\n                    <jats:styled-content style=\"fixed-case\">RDW<\/jats:styled-content>\n                    values (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.044). However,\n                    <jats:styled-content style=\"fixed-case\">RDW<\/jats:styled-content>\n                    did not show significant correlation with\n                    <jats:styled-content style=\"fixed-case\">PASI<\/jats:styled-content>\n                    (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.358). When patients were divided into two groups according to their\n                    <jats:styled-content style=\"fixed-case\">RDW<\/jats:styled-content>\n                    value (&lt;14.6% and \u226514.6%), the mean value of\n                    <jats:styled-content style=\"fixed-case\">PASI<\/jats:styled-content>\n                    was not significantly different (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.219). Patients with psoriasis showed increased\n                    <jats:styled-content style=\"fixed-case\">RDW<\/jats:styled-content>\n                    values compared with healthy controls. It was also higher in the moderate and severe disease group than the mild group. Though this is only a pilot study, it is possible that\n                    <jats:styled-content style=\"fixed-case\">RDW<\/jats:styled-content>\n                    value can reflect the inflammatory status of psoriasis patients.\n                  <\/jats:p>","DOI":"10.1111\/1346-8138.12865","type":"journal-article","created":{"date-parts":[[2015,3,26]],"date-time":"2015-03-26T17:43:55Z","timestamp":1427391835000},"page":"567-571","source":"Crossref","is-referenced-by-count":21,"title":["Red blood cell distribution width is increased in patients with psoriasis vulgaris: A retrospective study on 261 patients"],"prefix":"10.1111","volume":"42","author":[{"given":"Das Suk","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Dermatology Severance Hospital Cutaneous Biology Research Institute Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongyun","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of 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