{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T19:45:00Z","timestamp":1782935100715,"version":"3.54.5"},"reference-count":13,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2015,5,28]],"date-time":"2015-05-28T00:00:00Z","timestamp":1432771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Mycobacterium haemophilum<\/jats:italic> is a slow\u2010growing non\u2010tuberculous mycobacterium that is rarely known to cause human skin infection, particularly in immunocompromised patients. We recently experienced a 69\u2010year\u2010old Japanese woman with this infection who had been under immunosuppressive treatment for recalcitrant rheumatoid arthritis. The patient showed disseminated erythematous plaques and subcutaneous nodules on the face and extremities, and interestingly, the face manifested with a striking \u201cfacies leontina\u201d appearance. Biopsy revealed abscess and granulomatous dermatitis with the involvement of peripheral nerve bundles and the presence of innumerable acid\u2010fast bacilli, thus necessitating differentiation from lepromatous leprosy. <jats:italic>M.\u00a0haemophilum<\/jats:italic> was identified by molecular characterization as well as by successful culture with iron supplements. Although drug susceptibility testing indicated responsiveness to multiple antibiotics administrated simultaneously for the treatment, it took over 6\u00a0months to achieve significant improvement, and we also employed concurrent oral potassium iodide administration and repeated surgical excision. This case highlights the importance of continuous combination therapy for successful outcome in this rare infection. Furthermore, application of potassium iodide for mycobacterial infection warrants further evaluation by accumulating more cases.<\/jats:p>","DOI":"10.1111\/1346-8138.12948","type":"journal-article","created":{"date-parts":[[2015,5,28]],"date-time":"2015-05-28T17:44:10Z","timestamp":1432835050000},"page":"992-995","source":"Crossref","is-referenced-by-count":17,"title":["<i>Mycobacterium haemophilum<\/i> infection with prominent facial manifestation mimicking leprosy"],"prefix":"10.1111","volume":"42","author":[{"given":"Kentaro","family":"Ishii","sequence":"first","affiliation":[{"name":"Department of Dermatology National Hospital Organization Sagamihara National Hospital Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norihisa","family":"Ishii","sequence":"additional","affiliation":[{"name":"Leprosy Research Center National Institute of Infectious Diseases Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazue","family":"Nakanaga","sequence":"additional","affiliation":[{"name":"Leprosy Research Center National Institute of Infectious Diseases Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuaki","family":"Nakano","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory National Hospital Organization Sagamihara National Hospital Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikuo","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Pathology National Hospital Organization Sagamihara National Hospital Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiko","family":"Asahina","sequence":"additional","affiliation":[{"name":"Department of Dermatology National Hospital Organization Sagamihara National Hospital Kanagawa Japan"},{"name":"Department of Dermatology The Jikei University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,5,28]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(11)70029-9"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12047"},{"key":"e_1_2_5_4_1","volume-title":"Susceptibility Testing of Mycobacteria, Nocardiae, and Other Aerobic Actinomycetes; Approved Standard","author":"Woods GL"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00020-11"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2012.01533.x"},{"key":"e_1_2_5_7_1","first-page":"793127","article-title":"Mycobacterium haemophilum masquerading as leprosy in a renal transplant patient","volume":"2013","author":"Copeland NK","year":"2013","journal-title":"Case Rep Dermatol Med"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2013.09.003"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)15952-7"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20142450"},{"key":"e_1_2_5_11_1","first-page":"375","article-title":"Cutaneous mycobacterium chelonea subsp. infection in a ten\u2010year\u2010old boy","volume":"45","author":"Onouchi H","year":"2003","journal-title":"Rinsho Derma (Tokyo)"},{"key":"e_1_2_5_12_1","first-page":"249","article-title":"A case of Mycobacterium chelonei infection of the skin","volume":"37","author":"Arai H","year":"1983","journal-title":"Jpn J Clin Dermatol"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.95472"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20132377"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.12948","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.12948","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T14:05:37Z","timestamp":1695477937000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.12948"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,28]]},"references-count":13,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1111\/1346-8138.12948"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.12948","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,28]]}}}