{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T13:10:00Z","timestamp":1758892200942},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,7,16]],"date-time":"2015-07-16T00:00:00Z","timestamp":1437004800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The psychological aspect in patients with dystrophic epidermolysis bullosa (<jats:styled-content style=\"fixed-case\">DEB<\/jats:styled-content>) is poorly documented. We sought to determine the role of <jats:styled-content style=\"fixed-case\">DEB<\/jats:styled-content> in anxiety, depression and self\u2010esteem. We conducted a cross\u2010sectional study, collecting data from 27 <jats:styled-content style=\"fixed-case\">DEB<\/jats:styled-content> patients and 26 healthy individuals. <jats:styled-content style=\"fixed-case\">DEB<\/jats:styled-content> patients and healthy controls completed three different psychometric scales for anxiety and depression and one scale for self\u2010esteem. DEB patients and healthy controls were homogeneous for age and sex (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05), but not for employment, marital status and economic level (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). Median values of all psychometric battery scales were not statistically significant between <jats:styled-content style=\"fixed-case\">DEB<\/jats:styled-content> patients and healthy controls, except for Goldberg scale for anxiety (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.003) and depression (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.037) and slightly significant for Zung Scale for anxiety (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.048) with no difference between DEB patients with dominant versus recessive form in all scales (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05). Among <jats:styled-content style=\"fixed-case\">DEB<\/jats:styled-content> patients, only employment showed a significant difference in all scales (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05) but Hamilton for depression, whereas self\u2010esteem seemed to be affected by marriage (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.04) and education (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.016). <jats:styled-content style=\"fixed-case\">DEB<\/jats:styled-content> patients apparently are not more anxious and\/or depressed and do not have less self\u2010esteem than healthy individuals.<\/jats:p>","DOI":"10.1111\/1346-8138.13027","type":"journal-article","created":{"date-parts":[[2015,7,16]],"date-time":"2015-07-16T11:31:34Z","timestamp":1437046294000},"page":"70-78","source":"Crossref","is-referenced-by-count":11,"title":["Role of dystrophic epidermolysis bullosa in anxiety, depression and self\u2010esteem: A controlled cross\u2010sectional study"],"prefix":"10.1111","volume":"43","author":[{"given":"Giulio","family":"Fortuna","sequence":"first","affiliation":[{"name":"Department of Oral Medicine Carolinas Medical Center Charlotte North Carolina USA"},{"name":"D.eb.RA. Mexico Foundation Monterrey Nuevo Leon Mexico"},{"name":"School of Orgonomy \u201cPiero Borrelli\u201d Federico Navarro Institute Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Aria","sequence":"additional","affiliation":[{"name":"Department of Economics and Statistics Federico II University of Naples Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo","family":"Cepeda\u2010Valdes","sequence":"additional","affiliation":[{"name":"D.eb.RA. Mexico Foundation Monterrey Nuevo Leon Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra Cecilia","family":"Garcia\u2010Garcia","sequence":"additional","affiliation":[{"name":"D.eb.RA. Mexico Foundation Monterrey Nuevo Leon Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Guadalupe","family":"Moreno Trevino","sequence":"additional","affiliation":[{"name":"Department of Basic Science Universidad de Monterrey San Pedro Garza Garc\u00eda M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio Cesar","family":"Salas\u2010Alan\u00eds","sequence":"additional","affiliation":[{"name":"D.eb.RA. 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