{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T13:28:09Z","timestamp":1740144489137,"version":"3.37.3"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,9,2]],"date-time":"2015-09-02T00:00:00Z","timestamp":1441152000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Ministry of Health, Labor and Welfare (Research for Intractable Diseases)"},{"DOI":"10.13039\/501100001700","name":"the Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In patients with pemphigus vulgaris (PV), pathogenic immunoglobulin (Ig)G antibodies are most commonly directed against desmoglein 3 (Dsg3). It has recently been reported, however, that IgG anti\u2010desmocollin 3 (Dsc3) antibodies are detected in some cases of pemphigus with or without IgG anti\u2010Dsg3 antibodies. We present a case of pemphigus with IgG antibodies against Dsg3 and Dsc3. Subsequent studies showed that the cell surface distribution pattern of Dsc3 but not Dsg3 was altered, suggesting that suprabasal acantholytic blisters were induced by IgG anti\u2010Dsc3 antibodies rather than IgG anti\u2010Dsg3 antibodies. Our case suggests that anti\u2010Dsc3 antibodies may be pathogenic in cases positive for the dual cadherin autoantibodies.<\/jats:p>","DOI":"10.1111\/1346-8138.13086","type":"journal-article","created":{"date-parts":[[2015,9,2]],"date-time":"2015-09-02T20:31:32Z","timestamp":1441225892000},"page":"429-431","source":"Crossref","is-referenced-by-count":7,"title":["Atypical pemphigus with immunoglobulin G autoantibodies against desmoglein 3 and desmocollin 3"],"prefix":"10.1111","volume":"43","author":[{"given":"Koji","family":"Kamiya","sequence":"first","affiliation":[{"name":"Department of Dermatology Hamamatsu University School of Medicine Hamamatsu Japan"},{"name":"Department of Dermatology Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumi","family":"Aoyama","sequence":"additional","affiliation":[{"name":"Department of Dermatology Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan"},{"name":"Department of Dermatology Kawasaki Hospital Kawasaki Medical School Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chie","family":"Wakashima","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kochi Medical School Kochi University Nankoku Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoko","family":"Kudo","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kochi Medical School Kochi University Nankoku Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimiko","family":"Nakajima","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kochi Medical School Kochi University Nankoku Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigetoshi","family":"Sano","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kochi Medical School Kochi University Nankoku Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norito","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kurume University School of Medicine and Kurume University Institute of Cutaneous Cell Biology Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwesi","family":"Teye","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kurume University School of Medicine and Kurume University Institute of Cutaneous Cell Biology Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kurume University School of Medicine and Kurume University Institute of Cutaneous Cell Biology Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiji","family":"Iwatsuki","sequence":"additional","affiliation":[{"name":"Department of Dermatology Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Tokura","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hamamatsu University School of Medicine Hamamatsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,9,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1356"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12613668"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2010.100483"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.05995.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1684\/ejd.2012.1762","article-title":"Atypical pemphigus with exclusively anti\u2010desmocollin 3\u2010specific IgG antibodies","volume":"22","author":"Hatano Y","year":"2012","journal-title":"Eur J Dermatol"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12872"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12319025"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13711"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1006\/geno.1993.1453"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.031518"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2010.10.016"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.10929.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2013.02.011"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12906"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.13086","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.13086","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T14:02:46Z","timestamp":1695477766000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.13086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,2]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["10.1111\/1346-8138.13086"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.13086","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"type":"print","value":"0385-2407"},{"type":"electronic","value":"1346-8138"}],"subject":[],"published":{"date-parts":[[2015,9,2]]}}}