{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:39:28Z","timestamp":1761709168239},"reference-count":17,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2016,3,3]],"date-time":"2016-03-03T00:00:00Z","timestamp":1456963200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST 103\u20102314\u2010B\u2010182A\u2010020","MOST 102\u20102314\u2010B\u2010182\u2010053\u2010MY3"],"award-info":[{"award-number":["MOST 103\u20102314\u2010B\u2010182A\u2010020","MOST 102\u20102314\u2010B\u2010182\u2010053\u2010MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005795","name":"Chang Gung Memorial Hospital, Linkou","doi-asserted-by":"publisher","award":["CMRPG8C0821","CMRPG8C1081","CMRPG8D1541","CMRPG8B0211"],"award-info":[{"award-number":["CMRPG8C0821","CMRPG8C1081","CMRPG8D1541","CMRPG8B0211"]}],"id":[{"id":"10.13039\/501100005795","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>For the past decades, although the rash at the bacillus Calmette\u2013Gu\u00e9rin (<jats:styled-content style=\"fixed-case\">BCG<\/jats:styled-content>) inoculation site has been recognized as a diagnostic clue in Kawasaki disease, the present study is the first known one attempting to characterize <jats:styled-content style=\"fixed-case\">BCG<\/jats:styled-content> inoculation by dermatoscopy in Kawasaki disease and correlate the grade of <jats:styled-content style=\"fixed-case\">BCG<\/jats:styled-content> reaction with systemic involvement. Thirty\u2010four patients diagnosed with Kawasaki disease by pediatric specialists were enrolled. We performed detailed history taking, laboratory examination, physical examination and dermatoscopy examinations. Based on the <jats:styled-content style=\"fixed-case\">BCG<\/jats:styled-content> reaction pattern by dermatoscopy, we were able to characterize three patterns: (A) Bull's eye pattern in 18 patients; (B) faint homogenous erythema in nine; and (C) central white patch in seven. Patients from group A exhibited the highest elevation of blood aspartate aminotransferase levels (<jats:italic>P<\/jats:italic> &lt; 0.05). Notably, three patients from group A had a significantly dilated coronary artery despite i.v. immunoglobulin injection. We concluded that the bull's eye dermatoscopy sign is not only a useful diagnostic clue but also a severity biomarker in patients with Kawasaki disease.<\/jats:p>","DOI":"10.1111\/1346-8138.13315","type":"journal-article","created":{"date-parts":[[2016,3,3]],"date-time":"2016-03-03T10:35:19Z","timestamp":1457001319000},"page":"1044-1050","source":"Crossref","is-referenced-by-count":21,"title":["Bull's eye dermatoscopy pattern at bacillus Calmette\u2013Gu\u00e9rin inoculation site correlates with systemic involvements in patients with Kawasaki disease"],"prefix":"10.1111","volume":"43","author":[{"given":"Han\u2010Chi","family":"Tseng","sequence":"first","affiliation":[{"name":"Department of Dermatology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji\u2010Chen","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mindy Ming\u2010Huey","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung Taiwan"},{"name":"Kawasaki Disease Center Kaohsiung Chang Gung Memorial Hospital Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mao\u2010Hung","family":"Lo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung Taiwan"},{"name":"Kawasaki Disease Center Kaohsiung Chang Gung Memorial Hospital Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai\u2010Sheng","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kaohsiung Chang 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