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This study aimed to investigate complications of systemic propranolol therapy for infantile hemangiomas, especially its effect on infants' physical growth. In this study, propranolol was given at a dose of 2 mg\/kg per day. Abnormal symptoms and growth parameters were recorded in detail during the therapy. Follow\u2010up visits were arranged to continue at least through the age of 2 years. A total of 76 patients with complete growth parameters were enrolled into the study. Complications of propranolol were minor, and mainly included sleeping disorders, diarrhea, decrease in fasting glucose, bronchial hyperactivity and hyperkalemia. Four (5.26%) patients' growth curve dropped off more than 20 percentiles during therapy and half of them returned to normal after withdrawal of the medications. None of them suffered from underweight, wasting or stunning when medication was stopped. Systemic propranolol was proved to be a safe treatment for problematic infantile hemangiomas and did not affect the physical growth.<\/jats:p>","DOI":"10.1111\/1346-8138.13324","type":"journal-article","created":{"date-parts":[[2016,3,6]],"date-time":"2016-03-06T11:31:22Z","timestamp":1457263882000},"page":"1160-1166","source":"Crossref","is-referenced-by-count":11,"title":["Effects of systemic propranolol treatment on physical growth of patients with infantile hemangiomas"],"prefix":"10.1111","volume":"43","author":[{"given":"Li","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bingrui","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Children's Health Care Children's Hospital Fudan University Shanghai 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