{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T19:24:53Z","timestamp":1785093893630,"version":"3.55.0"},"reference-count":28,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,3,19]],"date-time":"2016-03-19T00:00:00Z","timestamp":1458345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005120","name":"Japan Nuclear Cycle Development Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005120","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The Dermatophyte Test Strip visualizes mycotic antigens by immunochromatography. It allows easy and fast detection of dermatophytes. A multicenter, single\u2010arm, comparative clinical study was designed to evaluate the capacity of Dermatophyte Test Strip to detect dermatophytes in suspected tinea unguium specimens in comparison with direct microscopy and polymerase chain reaction (<jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content>). Signed consent was obtained from 222 subjects and all subjects completed the study. With the Dermatophyte Test Strip, dermatophytes were detected in 201 of 222 (90.5%) specimens but not in 21 of 222 (9.5%) specimens. With direct microscopy, dermatophytes were detected in 170 of 222 (76.6%) specimens but not in 52 of 222 (23.4%). Of the 45 specimens that showed inconsistent results between the two methods, <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> gave further results for 40 specimens, of which 37 (92.5%) specimens were positive and three (7.5%) were negative for dermatophytes. The positive concordance rate, negative concordance rate and overall concordance rate between the Dermatophyte Test Strip and direct microscopy were 81.1%, 66.7% and 79.7%, respectively. When inconsistent results were corrected using the results of <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content>, these rates were 97.5%, 71.4% and 95.0%, respectively. When five specimens that could not be tested by <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> because no piece for the <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> test was left were excluded from analysis, these rates were 99.0%, 78.9% and 97.2%, respectively. The present results indicate good detection capacity of the Dermatophyte Test Strip. The Dermatophyte Test Strip provides a reliable, convenient and quick method to test for tinea unguium.<\/jats:p>","DOI":"10.1111\/1346-8138.13348","type":"journal-article","created":{"date-parts":[[2016,3,19]],"date-time":"2016-03-19T10:37:35Z","timestamp":1458383855000},"page":"1417-1423","source":"Crossref","is-referenced-by-count":39,"title":["Clinical study of Dermatophyte Test Strip, an immunochromatographic method, to detect tinea unguium dermatophytes"],"prefix":"10.1111","volume":"43","author":[{"given":"Yuichiro","family":"Tsunemi","sequence":"first","affiliation":[{"name":"Department of Dermatology Tokyo Women's Medical University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masataro","family":"Hiruma","sequence":"additional","affiliation":[{"name":"Ochanomizu Institute for Medical Mycology and Allergology Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,3,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2009.00741.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2710.2009.01107.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.12245_suppl"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546630310012109"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2009.12.001"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mycmed.2014.11.002"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2009.12.006"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.149.s65.4.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2005.01287.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.2007.00320.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12660"},{"key":"e_1_2_7_13_1","unstructured":"KajitaniK NorikiS IshidaH inventers; Toyobo Co. 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