{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:39:48Z","timestamp":1787013588688,"version":"build-2736575974"},"reference-count":9,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2016,4,20]],"date-time":"2016-04-20T00:00:00Z","timestamp":1461110400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Various systemic corticosteroid therapies are used for alopecia areata (\n                    <jats:styled-content style=\"fixed-case\">AA<\/jats:styled-content>\n                    ). Pulse therapy using methylprednisolone is a treatment approach for\n                    <jats:styled-content style=\"fixed-case\">AA<\/jats:styled-content>\n                    . The efficacy of multiple courses of pulse therapy for various severities of\n                    <jats:styled-content style=\"fixed-case\">AA<\/jats:styled-content>\n                    was evaluated.\n                    <jats:styled-content style=\"fixed-case\">AA<\/jats:styled-content>\n                    patients with less than 50% hair loss, less than or equal to 6 months after\n                    <jats:styled-content style=\"fixed-case\">AA<\/jats:styled-content>\n                    onset, needed 1.9 courses of pulse therapy for vellus hair to develop. On the other hand,\n                    <jats:styled-content style=\"fixed-case\">AA<\/jats:styled-content>\n                    patients with more than 50% hair loss, less than 6 months after\n                    <jats:styled-content style=\"fixed-case\">AA<\/jats:styled-content>\n                    onset, needed more courses of pulse therapy for vellus hair to develop. Regardless of the disease duration,\n                    <jats:styled-content style=\"fixed-case\">AA<\/jats:styled-content>\n                    patients with less than 50% hair loss showed a good response rate (100%) after both a short period and a long period after therapy. After receiving multiple courses of pulse therapy, the\n                    <jats:styled-content style=\"fixed-case\">AA<\/jats:styled-content>\n                    patients with more than 50% hair loss also showed improvement with limited adverse reactions.\n                  <\/jats:p>","DOI":"10.1111\/1346-8138.13388","type":"journal-article","created":{"date-parts":[[2016,4,20]],"date-time":"2016-04-20T02:19:18Z","timestamp":1461118758000},"page":"1075-1077","source":"Crossref","is-referenced-by-count":14,"title":["Multiple courses of pulse corticosteroid therapy for alopecia areata"],"prefix":"10.1111","volume":"43","author":[{"given":"Takashi","family":"Yoshimasu","sequence":"first","affiliation":[{"name":"Department of Dermatology Wakayama Medical University Wakayama Japan"},{"name":"Department of Dermatology Arida Municipal Hospital Arida Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuo","family":"Kanazawa","sequence":"additional","affiliation":[{"name":"Department of Dermatology Wakayama Medical University Wakayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Dermatology Wakayama Medical University Wakayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fukumi","family":"Furukawa","sequence":"additional","affiliation":[{"name":"Department of Dermatology Wakayama Medical University Wakayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,4,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.10955.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000107626"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2003.09.032"},{"key":"e_1_2_6_5_1","first-page":"514","article-title":"Treatment of alopecia areata with prednisone in a once\u2010monthly oral pulse","volume":"137","author":"Ait OM","year":"2010","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_6_6_1","first-page":"310","article-title":"Medium\u2010dose prednisolone pulse therapy in alopecia areata","volume":"6","author":"Efentaki P","year":"2009","journal-title":"Dermatoendocrinol"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000051642"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/09546634.2013.768759"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2010.01135.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000066435"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.13388","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.13388","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T06:52:44Z","timestamp":1695538364000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.13388"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,20]]},"references-count":9,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1111\/1346-8138.13388"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.13388","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,20]]}}}