{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T20:11:55Z","timestamp":1778443915435,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T00:00:00Z","timestamp":1469059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>Partial unilateral lentiginosis (<jats:styled-content style=\"fixed-case\">PUL<\/jats:styled-content>) is a rare pigmentation disorder characterized by numerous lentigines with sharp margins in the midline in one or more dermatomes. Its segmental pattern suggests that this presentation accompanied by caf\u00e9\u2010au\u2010lait spots, Lisch nodule or neurofibromas has a close relationship with mosaic neurofibromatosis type 1 or segmental neurofibromatosis (<jats:styled-content style=\"fixed-case\">NF<\/jats:styled-content>) in particular.<\/jats:p><\/jats:sec><jats:sec><jats:label\/><jats:p>In a group of 16 patients with <jats:styled-content style=\"fixed-case\">PUL<\/jats:styled-content>, who presented at the dermatology outpatient clinic between 1998 and 2015, an examination was made of consanguineous marriage in the family history, the presence of a similar lesion or <jats:styled-content style=\"fixed-case\">NF<\/jats:styled-content> in first\u2010degree relatives, neurofibroma in the physical examination, the involvement pattern, axillary\/inguinal freckling and the presence and number of caf\u00e9\u2010au\u2010lait spots. The ophthalmological examination investigated Lisch nodule and optic glioma. The skeletal system was examined for <jats:styled-content style=\"fixed-case\">NF<\/jats:styled-content> involvement.<\/jats:p><\/jats:sec><jats:sec><jats:label\/><jats:p>Of 16 patients, 13 (81.2%) were female and three (18.8%) were male with a mean age of 31.19 years (range, 15\u201348). There was no family history of <jats:styled-content style=\"fixed-case\">PUL<\/jats:styled-content> in any case. Consanguineous marriage was absent in 15 patients (93.8%). While there were accompanying caf\u00e9\u2010au\u2010lait spots in three patients (18.8%). Lisch nodule was an accompanying finding in three patients (18.8%). Axillary freckling was detected in four (25%) patients. Neurofibroma was found in only one patient.<\/jats:p><\/jats:sec><jats:sec><jats:label\/><jats:p>Although caf\u00e9\u2010au\u2010lait spots, axillary freckling, neurofibroma and Lisch nodule were present in a small number of the patients, the presence of the findings may be considered to be specific to <jats:styled-content style=\"fixed-case\">NF<\/jats:styled-content> suggests that <jats:styled-content style=\"fixed-case\">PUL<\/jats:styled-content> is a variant of mosaic <jats:styled-content style=\"fixed-case\">NF<\/jats:styled-content>\u20101. Genetic studies will help to further elucidate this subject.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1346-8138.13510","type":"journal-article","created":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T05:53:18Z","timestamp":1469080398000},"page":"29-35","source":"Crossref","is-referenced-by-count":8,"title":["Partial unilateral lentiginosis is mosaic neurofibromatosis type 1 or not?"],"prefix":"10.1111","volume":"44","author":[{"given":"\u015eirin","family":"Ya\u015far","sequence":"first","affiliation":[{"name":"Department of Dermatology Haydarpasa Numune Training and Research Hospital Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ay\u015feg\u00fcl","family":"Ersanli","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Haydarpasa Numune Training and Research Hospital Istanbul 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