{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T01:38:25Z","timestamp":1768268305894,"version":"3.49.0"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,10,15]],"date-time":"2016-10-15T00:00:00Z","timestamp":1476489600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100012351","name":"Mitsubishi-Tanabe Pharma","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100012351","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Esai"},{"name":"Abbvie Japan"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a case of a 70\u2010year\u2010old woman with generalized pustular psoriasis (<jats:styled-content style=\"fixed-case\">GPP<\/jats:styled-content>) who responded well to infliximab therapy and adalimumab therapy after secondary failure of infliximab therapy, but did not respond to ustekinumab therapy. We speculate that the pathogenic factor in this case favored anti\u2010tumor necrosis factor (<jats:styled-content style=\"fixed-case\">TNF<\/jats:styled-content>)\u2010\u03b1 therapy to anti\u2010interleukin\u201012\/23 therapy. Herein, we also briefly present three additional cases of treatment with adalimumab after secondary failure of infliximab. <jats:styled-content style=\"fixed-case\">GPP<\/jats:styled-content> is often difficult to treat, and no placebo\u2010controlled trials have been conducted to guide the use of biologics against it because of a paucity of cases. Infliximab and adalimumab are anti\u2010<jats:styled-content style=\"fixed-case\">TNF<\/jats:styled-content>\u2010\u03b1 antibodies that specifically block the interaction of <jats:styled-content style=\"fixed-case\">TNF<\/jats:styled-content>\u2010\u03b1 with its receptors. Infliximab has been reported to be effective, with a rapid clearance of symptoms, even in cases of severe <jats:styled-content style=\"fixed-case\">GPP<\/jats:styled-content>. Adalimumab could be a good biologic candidate that can be administrated after secondary failure of infliximab therapy.<\/jats:p>","DOI":"10.1111\/1346-8138.13632","type":"journal-article","created":{"date-parts":[[2016,10,15]],"date-time":"2016-10-15T07:02:50Z","timestamp":1476514970000},"page":"202-204","source":"Crossref","is-referenced-by-count":27,"title":["Adalimumab administration after infliximab therapy is a successful treatment strategy for generalized pustular psoriasis"],"prefix":"10.1111","volume":"44","author":[{"given":"Ai","family":"Matsumoto","sequence":"first","affiliation":[{"name":"Department of Dermatology Jichi Medical University Shimotsuke Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayumi","family":"Komine","sequence":"additional","affiliation":[{"name":"Department of Dermatology Jichi Medical University Shimotsuke Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaru","family":"Karakawa","sequence":"additional","affiliation":[{"name":"Department of Dermatology Jichi Medical University Shimotsuke Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megumi","family":"Kishimoto","sequence":"additional","affiliation":[{"name":"Department of Dermatology Jichi Medical University Shimotsuke Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mamitaro","family":"Ohtsuki","sequence":"additional","affiliation":[{"name":"Department of Dermatology Jichi Medical University Shimotsuke Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,10,15]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"815","article-title":"Guideline for generalized pustular psoriasis 2010","volume":"120","author":"Iwatsuki K","year":"2010","journal-title":"Jpn Dermatol Assoc J"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.01.032"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2012.01563.x"},{"key":"e_1_2_5_5_1","first-page":"342","article-title":"Biologic therapy in erythroderumic and pustular psoriasis","volume":"13","author":"Levin EC","year":"2014","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546630500430604"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/2013.jamadermatol.80"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546630701759587"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12597"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12704"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09995.x"},{"key":"e_1_2_5_12_1","first-page":"1240","article-title":"Treatment of severe psoriasis with ustekinumab during pregnancy","volume":"11","author":"Andrulonis R","year":"2012","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12392"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.3109\/09546634.2010.534430"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.11209.x"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09505.x"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.13632","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.13632","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.13632","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T15:08:28Z","timestamp":1695568108000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.13632"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,15]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["10.1111\/1346-8138.13632"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.13632","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,15]]}}}