{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:28:35Z","timestamp":1790659715311,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,10,15]],"date-time":"2016-10-15T00:00:00Z","timestamp":1476489600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The standard management of acne vulgaris in Japan includes a combination of topical treatment with benzoyl peroxide (BPO) and BPO\/clindamycin (CLDM), topical adapalene and systemic antimicrobials. However, the treatment of therapy\u2010resistant complications such as postinflammatory hyperpigmentation (PIH), erosions with inflamed red papules and atrophic scars has not been established. We performed chemical peeling with glycolic acid and iontophoresis with ascorbyl 2\u2010phosphate 6\u2010palmitate and DL\u2010\u03b1\u2010tocopherol phosphate for the treatment of PIH, erosions with inflamed red papules and non\u2010inflamed atrophic scars in 31 patients with acne vulgaris (mild to severe severity), and evaluated the efficacy and safety of these interventions. In most of cases, there was remarkable improvement in PIH and erosions with inflamed red papules after treatment. There was also some improvement in non\u2010inflamed atrophic scars without erythema. Mild redness and irritation was observed in four cases as adverse reactions. Early initial treatment of PIH and erosions with red papules by chemical peeling and iontophoresis is an effective and safe method to prevent the formation of atrophic scars in patients with acne vulgaris.<\/jats:p>","DOI":"10.1111\/1346-8138.13634","type":"journal-article","created":{"date-parts":[[2016,10,15]],"date-time":"2016-10-15T07:36:52Z","timestamp":1476517012000},"page":"401-405","source":"Crossref","is-referenced-by-count":18,"title":["Adjuvant alternative treatment with chemical peeling and subsequent iontophoresis for postinflammatory hyperpigmentation, erosion with inflamed red papules and non\u2010inflamed atrophic scars in acne vulgaris"],"prefix":"10.1111","volume":"44","author":[{"given":"Ichiro","family":"Kurokawa","sequence":"first","affiliation":[{"name":"Department of Dermatology and Acne Clinical Research Center Meiwa Hospital Nishinomiya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Oiso","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Kinki University Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Kawada","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Kinki University Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,10,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2009.00890.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13263"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12050"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13044"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0625.12.s2.7.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2011.01362.x"},{"key":"e_1_2_6_8_1","first-page":"49","volume-title":"Acne \u2013 Diagnosis and Management","author":"Cunliffe WJ","year":"2001"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2007.00403.x-i1"},{"key":"e_1_2_6_10_1","first-page":"19","volume-title":"Acne","author":"Layton A","year":"2004"},{"key":"e_1_2_6_11_1","first-page":"1045","article-title":"Guideline for the treatment of acne vulgaris 2016","volume":"126","author":"Hayashi N","year":"2016","journal-title":"Jpn J Dermatol"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0625.12.s2.9.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2011.01321.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12864"},{"key":"e_1_2_6_15_1","first-page":"1","article-title":"The efficacy and safety of subcision using CO2 gas combined with fractional laser for acne scars: clinical and microscopic evaluation","volume":"28","author":"Lee SJ","year":"2016","journal-title":"J Cosmet Laser Ther"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2011.3063"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04330.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1994.tb01200.x"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.13634","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.13634","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.13634","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T12:37:15Z","timestamp":1695472635000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.13634"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,15]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["10.1111\/1346-8138.13634"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.13634","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,15]]}}}