{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T01:34:58Z","timestamp":1794360898828,"version":"4.9.0"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,10,27]],"date-time":"2016-10-27T00:00:00Z","timestamp":1477526400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008904","name":"Taipei Hospital","doi-asserted-by":"publisher","award":["R\u201011004"],"award-info":[{"award-number":["R\u201011004"]}],"id":[{"id":"10.13039\/100008904","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The association between sarcoidosis and autoimmune comorbidities has been reported, however, it has seldom been confirmed by a large nationwide study. Our study aimed to clarify the association between sarcoidosis and autoimmune comorbidities in the Taiwanese. A total of 1237 patients with sarcoidosis and 4948 age\u2010 and sex\u2010matched control subjects were selected from the National Health Insurance Research Database of Taiwan from 1997 to 2010. Multiple logistic regressions were performed to calculate the odds of comorbidities between the two groups. The prevalence of sarcoidosis was 2.17\/100\u00a0000 individuals in Taiwan. Sarcoidosis patients tended to run a higher risk of autoimmune comorbidities than the control group (17.6% vs 9.4%,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0&lt;\u00a00.05). Autoimmune thyroid disease (adjusted odd ratio [\n                    <jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\n                    ], 1.32; 95% confidence interval [\n                    <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                    ], 1.05\u20131.64), Sj\u00f6gren's syndrome (\n                    <jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\n                    , 11.6; 95%\n                    <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                    , 4.36\u201331.0) and ankylosing spondylitis (\n                    <jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\n                    , 3.80; 95%\n                    <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                    , 2.42\u20135.97) were significantly associated with sarcoidosis. The sex\u2010stratified analyses were carried out to demonstrate a significant association of sarcoidosis with ankylosing spondylitis in both sexes, but with autoimmune thyroid disease in male patients and with Sj\u00f6gren's syndrome female patients, respectively. Besides, the diagnosis of the autoimmune comorbidities strongly associated with sarcoidosis tended to be established after that of sarcoidosis. This study demonstrated that patients with sarcoidosis tended to have autoimmune thyroid disease, Sj\u00f6gren's syndrome and ankylosing spondylitis, and the diagnosis of sarcoidosis usually preceded that of associated comorbidities. Clinicians should be alert to autoimmune comorbidities in patients with sarcoidosis.\n                  <\/jats:p>","DOI":"10.1111\/1346-8138.13654","type":"journal-article","created":{"date-parts":[[2016,10,27]],"date-time":"2016-10-27T05:13:10Z","timestamp":1477545190000},"page":"423-430","source":"Crossref","is-referenced-by-count":97,"title":["Comorbid autoimmune diseases in patients with sarcoidosis: A nationwide case\u2013control study in Taiwan"],"prefix":"10.1111","volume":"44","author":[{"given":"Chi\u2010Hung","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Dermatology Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Dermatology National Yang\u2010Ming University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei\u2010I.","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Dermatology Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Dermatology National Yang\u2010Ming University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen\u2010Yi","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Institute of Public Health and Department of Public Health National Yang\u2010Ming University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yen\u2010Ta","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Dermatology National Yang\u2010Ming University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun\u2010Wen","family":"Chiu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Dermatology National Yang\u2010Ming University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun\u2010Ting","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Dermatology National Yang\u2010Ming University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han\u2010Nan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Dermatology National Yang\u2010Ming University Taipei Taiwan"},{"name":"Department of Dermatology National Defense Medical Center Taipei 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