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Therefore we investigated the presence of anti\u2010\u03b16\u2010integrin autoantibodies in the serum of patients with psoriasis vulgaris (Ps), psoriatic arthritis (PsA) and rheumatoid arthritis (<jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content>) in comparison with healthy donors. The level of circulating anti\u2010\u03b16\u2010integrin antibodies was determined by enzyme\u2010linked immunoassay using \u03b16\u2010integrin fragments. Antibodies against at least one recombinant fragment were found in approximately 30% of Ps and PsA patients. In contrast, in <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content> patients, the frequency of antibodies was similar to healthy controls. Our study shows the presence of anti\u2010\u03b16\u2010integrin antibodies in Ps and PsA but not in <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content>, which could indicate ongoing abnormal processes in the skin. Anti\u2010\u03b16\u2010integrin autoantibodies may contribute to the formation of micro\u2010wounds in the skin and to the characteristic wound\u2010healing phenotype in psoriasis.<\/jats:p>","DOI":"10.1111\/1346-8138.13667","type":"journal-article","created":{"date-parts":[[2016,10,28]],"date-time":"2016-10-28T06:54:50Z","timestamp":1477637690000},"page":"370-374","source":"Crossref","is-referenced-by-count":17,"title":["Increased circulating anti\u2010\u03b16\u2010integrin autoantibodies in psoriasis and psoriatic arthritis but not in rheumatoid arthritis"],"prefix":"10.1111","volume":"44","author":[{"given":"Brigitta","family":"G\u00e1l","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergology University of Szeged Szeged Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonja","family":"Dulic","sequence":"additional","affiliation":[{"name":"Department of Rheumatology University of Szeged Szeged 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