{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:28:09Z","timestamp":1756384089505,"version":"3.37.3"},"reference-count":13,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,8,3]],"date-time":"2017-08-03T00:00:00Z","timestamp":1501718400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2017,12]]},"abstract":"Abstract<\/jats:title>A male fetus was delivered by cesarean section with a large hemangioma on his right chest and thrombocytopenia. Clinically, Kasabach\u2013Merritt syndrome (KMS<\/jats:styled-content>) was suspected, and immediately he was treated with daily prednisolone (PSL<\/jats:styled-content>) 1 mg\/kg and recombinant thrombomodulin without response. Additional propranolol (1\u20133 mg\/kg per day) and increased PSL<\/jats:styled-content> 2 mg\/kg per day therapy successfully controlled his disseminated intravascular coagulation and decreased the tumor size without serious side\u2010effects. No relapse of KMS<\/jats:styled-content> was observed after cease of PSL<\/jats:styled-content> and propranolol. Combined use of propranolol and corticosteroid is expected as a candidate therapeutic tool for KMS<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/1346-8138.13984","type":"journal-article","created":{"date-parts":[[2017,8,3]],"date-time":"2017-08-03T19:38:40Z","timestamp":1501789120000},"page":"1389-1391","source":"Crossref","is-referenced-by-count":7,"title":["Successful combination therapy of propranolol and prednisolone for a case with congenital Kasabach\u2013Merritt syndrome"],"prefix":"10.1111","volume":"44","author":[{"given":"Kento","family":"Mizutani","sequence":"first","affiliation":[{"name":"Department of Dermatology Yokkaichi Municipal Hospital Yokkaichi Japan"},{"name":"Department of Dermatology Faculty of Medicine Mie University Tsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai","family":"Umaoka","sequence":"additional","affiliation":[{"name":"Department of Dermatology Yokkaichi Municipal Hospital Yokkaichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenshiro","family":"Tsuda","sequence":"additional","affiliation":[{"name":"Department of Dermatology Yokkaichi Municipal Hospital Yokkaichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masato","family":"Kakeda","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Mie University Tsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Habe","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Mie University Tsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3055-5202","authenticated-orcid":false,"given":"Keiichi","family":"Yamanaka","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Mie University Tsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megumi","family":"Suyama","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Yokkaichi Municipal Hospital Yokkaichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Mizutani","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Mie University Tsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,8,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(97)70249-X"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199711000-00001"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2012.06.044"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2001.02453.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a006460"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2013.03.080"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-013-1549-3"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc0708819"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0138100"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.epsc.2013.05.018"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e3182152e4e"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.24103"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2010.01224.x"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.13984","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.13984","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T15:38:19Z","timestamp":1695483499000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.13984"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,3]]},"references-count":13,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["10.1111\/1346-8138.13984"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.13984","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"type":"print","value":"0385-2407"},{"type":"electronic","value":"1346-8138"}],"subject":[],"published":{"date-parts":[[2017,8,3]]}}}