{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T12:40:16Z","timestamp":1760013616673,"version":"3.37.3"},"reference-count":7,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2018,1]]},"abstract":"Abstract<\/jats:title>Various patterns of nail plate destruction are common features in subungual melanoma (SUM<\/jats:styled-content>), but there has been no reports regarding their clinical significance according to the pattern of nail plate destruction in terms of tumor thickness. We tried to find a relationship between dermal invasion of SUM<\/jats:styled-content> and proximal nail plate destruction (PNPD<\/jats:styled-content>). Clinical information of patients with SUM<\/jats:styled-content> was reviewed retrospectively from seven dermatology training hospitals in Korea. The PNPD<\/jats:styled-content> was defined as a visible loss of full thickness of nail plate touching the eponychium at the most proximal part of it. We evaluated whether there are correlations between patients' age, sex, location of SUM<\/jats:styled-content>, Breslow thickness (BT<\/jats:styled-content>) and the presence of PNPD<\/jats:styled-content>. Among 93 patients with SUM<\/jats:styled-content>, 36 (38.7%) showed PNPD<\/jats:styled-content>. Sex and BT<\/jats:styled-content> showed significant correlations with the presence of PNPD<\/jats:styled-content> in univariate analysis (P<\/jats:italic> < 0.05). BT<\/jats:styled-content>, age and sex showed significant correlations with the presence of PNPD<\/jats:styled-content> in multivariate analysis (P<\/jats:italic> < 0.05). Among them, BT<\/jats:styled-content> showed the strongest correlation with the presence of PNPD<\/jats:styled-content> (area under the curve, 0.722) and the cut\u2010off value was 1.25 mm. In conclusion, we suggest that PNPD<\/jats:styled-content> in SUM<\/jats:styled-content> could be a possible predictor of invasiveness of more than 1.25 mm BT<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/1346-8138.14027","type":"journal-article","created":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T09:32:41Z","timestamp":1504258361000},"page":"83-86","source":"Crossref","is-referenced-by-count":4,"title":["Proximal nail plate destruction in subungual melanoma could be a possible predictor of invasiveness thicker than 1.25 mm"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2999-1018","authenticated-orcid":false,"given":"Jun Young","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Dermatology Kyungpook National University School of Medicine Daegu Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moon\u2010Bum","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Pusan National University School of Medicine Busan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Byung Cheol","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Dermatology College of Medicine Dankook University Cheonan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kee Yang","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Dermatology Severance Hospital Yonsei University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"You Chan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Ajou University School of Medicine Suwon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sook Jung","family":"Yun","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chonnam National University Medical School Gwangju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chong Hyun","family":"Won","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Man\u2010Hoon","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Pathology Kyungpook National University School of Medicine Daegu Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won Kee","family":"Lee","sequence":"additional","affiliation":[{"name":"Center of Biostatistics Kyungpook National University School of Medicine Daegu Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seok\u2010Jong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kyungpook National University School of Medicine Daegu Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,9]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"149","article-title":"Clinicopathological features of cutaneous malignant melanoma","volume":"45","author":"Park KD","year":"2007","journal-title":"Korean J Dermatol"},{"doi-asserted-by":"publisher","key":"e_1_2_6_3_1","DOI":"10.1046\/j.1365-2133.1996.19754.x"},{"doi-asserted-by":"publisher","key":"e_1_2_6_4_1","DOI":"10.1016\/j.jaad.2015.04.044"},{"unstructured":"Nccn.org [homepage on the internet]. Fort Washington: NCCN Guidelines Version 1.2017 Melanoma Inc.;2016[Cited 11 Oct 2016.] Available from URL:http:\/\/www.nccn.org\/.","key":"e_1_2_6_5_1"},{"doi-asserted-by":"publisher","key":"e_1_2_6_6_1","DOI":"10.1159\/000329432"},{"doi-asserted-by":"publisher","key":"e_1_2_6_7_1","DOI":"10.1111\/1346-8138.12622"},{"doi-asserted-by":"publisher","key":"e_1_2_6_8_1","DOI":"10.1046\/j.1524-4725.2003.29087.x"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.14027","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.14027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T16:23:22Z","timestamp":1695572602000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.14027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1111\/1346-8138.14027"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.14027","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"type":"print","value":"0385-2407"},{"type":"electronic","value":"1346-8138"}],"subject":[],"published":{"date-parts":[[2017,9]]}}}