{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T11:20:47Z","timestamp":1778498447487,"version":"3.51.4"},"reference-count":9,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,11,30]],"date-time":"2017-11-30T00:00:00Z","timestamp":1512000000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Aggressive digital papillary adenocarcinoma (<jats:styled-content style=\"fixed-case\">ADPA<\/jats:styled-content>) is a rare cutaneous tumor with sweat gland differentiation. Due to the high risk of local recurrence and delayed metastasis, the wide local resection of the primary lesion and long\u2010term follow up are recommended for <jats:styled-content style=\"fixed-case\">ADPA<\/jats:styled-content>. Here, we report two cases of <jats:styled-content style=\"fixed-case\">ADPA<\/jats:styled-content>. Case 1 had a blue\u2010gray nodule on the tip of the right middle finger. Case 2 had had a papule on the dorsal side of the left ring finger for 13 years. In both cases, papillary proliferations of the tumor cells showed multilobular adenomatous structures with back\u2010to\u2010back patterns characteristic of <jats:styled-content style=\"fixed-case\">ADPA<\/jats:styled-content>. We amputated the finger at the proximal interphalangeal joint and performed a wide resection of the primary tumor in Case 1 and 2, respectively. Sentinel lymph node biopsy in the axilla was performed, and no sentinel lymph node metastasis was found in either case. Among the previously reported <jats:styled-content style=\"fixed-case\">ADPA<\/jats:styled-content> cases, clinically, most lesions were skin\u2010colored or tan\u2010brown to gray. The blue\u2010gray color in Case 1 is thought to be extraordinary for <jats:styled-content style=\"fixed-case\">ADPA<\/jats:styled-content>. In Case 2, the patient had had the small lesion for more than 13 years and the tumor size had been stable during that long period. The present two cases suggest that <jats:styled-content style=\"fixed-case\">ADPA<\/jats:styled-content> shows a prominent variety of both clinical features and disease courses, and that we cannot exclude the possibility of <jats:styled-content style=\"fixed-case\">ADPA<\/jats:styled-content> even in cases of blue\u2010gray nodules or small, stable, non\u2010progressive papules.<\/jats:p>","DOI":"10.1111\/1346-8138.14159","type":"journal-article","created":{"date-parts":[[2017,11,30]],"date-time":"2017-11-30T12:22:45Z","timestamp":1512044565000},"page":"357-360","source":"Crossref","is-referenced-by-count":6,"title":["Highly variable clinical feature and course of aggressive digital papillary adenocarcinoma"],"prefix":"10.1111","volume":"45","author":[{"given":"Kenji","family":"Yokota","sequence":"first","affiliation":[{"name":"Department of Dermatology Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2639-1583","authenticated-orcid":false,"given":"Michihiro","family":"Kono","sequence":"additional","affiliation":[{"name":"Department of Dermatology Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazue","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiro","family":"Sakakibara","sequence":"additional","affiliation":[{"name":"Division of Dermatology Anjo Kosei Hospital Anjo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5863-9315","authenticated-orcid":false,"given":"Masashi","family":"Akiyama","sequence":"additional","affiliation":[{"name":"Department of Dermatology Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,11,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.02.028"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1987.tb00488.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200006000-00002"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31826320ec"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAT.0b013e32835af778"},{"key":"e_1_2_5_7_1","first-page":"143","article-title":"Aggressive digital papillary adenocarcinoma \u2010 a rare malignant tumor of the sweat glands: two case reports and a review of the literature","volume":"8","author":"Altmann S","year":"2015","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000000703"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.07.038"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JHSB.2006.12.012"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.14159","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.14159","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T04:01:57Z","timestamp":1694491317000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.14159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,30]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1111\/1346-8138.14159"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.14159","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,30]]}}}