{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:39:49Z","timestamp":1787013589816,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,1,16]],"date-time":"2018-01-16T00:00:00Z","timestamp":1516060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2018,4]]},"abstract":"Abstract<\/jats:title>\n \n Primary scarring alopecia (\n PSA<\/jats:styled-content>\n ) is caused by irreversible damage to the hair epithelial stem cells that reside in hair follicles. There is limited published work regarding\n PSA<\/jats:styled-content>\n amongst the Asian population. The aim of this study was to evaluate the clinical features and to characterize the subtypes of\n PSA<\/jats:styled-content>\n in southern Taiwan. In this retrospective case series, we reviewed 89 patients with pathology\u2010confirmed\n PSA<\/jats:styled-content>\n . The data was collected from National Cheng Kung University Hospital between 1988 through 2016. The clinical and histological data were reviewed, and the patients were characterized into different subtypes of\n PSA<\/jats:styled-content>\n based on the clinical features and histological findings. We noted seven different subtypes of\n PSA<\/jats:styled-content>\n . The most common type was dissecting cellulitis (\n DC<\/jats:styled-content>\n ) (30.3%), followed by lichen planopilaris (\n LPP<\/jats:styled-content>\n ) (23.5%), central centrifugal cicatricial alopecia (\n CCCA<\/jats:styled-content>\n ) (12.4%) and acne keloidalis nuchae (\n AKN<\/jats:styled-content>\n ) (12.4%). The other subtypes include folliculitis decalvans (\n FD<\/jats:styled-content>\n ), discoid lupus erythematosus (\n DLE<\/jats:styled-content>\n ) and pseudopelade of Brocq (\n PPB<\/jats:styled-content>\n ). Interestingly,\n FD<\/jats:styled-content>\n ,\n DC<\/jats:styled-content>\n and\n AKN<\/jats:styled-content>\n were more common in males, while\n CCCA<\/jats:styled-content>\n ,\n LPP<\/jats:styled-content>\n ,\n DLE<\/jats:styled-content>\n and\n PPB<\/jats:styled-content>\n had a female predominance. The mean age of patients with\n DLE<\/jats:styled-content>\n ,\n DC<\/jats:styled-content>\n and\n AKN<\/jats:styled-content>\n were younger, while patients with\n CCCA<\/jats:styled-content>\n ,\n LPP<\/jats:styled-content>\n ,\n PPB<\/jats:styled-content>\n and\n FD<\/jats:styled-content>\n tend to be older. The pattern of hair loss was more likely to be unifocal\u2010ragged border in\n CCCA<\/jats:styled-content>\n and\n DLE<\/jats:styled-content>\n , multifocal\u2010interconnected in\n LPP<\/jats:styled-content>\n and\n FD<\/jats:styled-content>\n , and multifocal\u2010separated in\n DC<\/jats:styled-content>\n . The pathogenesis of\n PSA<\/jats:styled-content>\n may be influenced by sex, age and genetic background. It is important to identify the hair loss pattern to differentiate the subtypes of\n PSA<\/jats:styled-content>\n .\n <\/jats:p>","DOI":"10.1111\/1346-8138.14217","type":"journal-article","created":{"date-parts":[[2018,1,16]],"date-time":"2018-01-16T23:22:40Z","timestamp":1516144960000},"page":"450-455","source":"Crossref","is-referenced-by-count":24,"title":["Primary scarring alopecia: A retrospective study of 89 patients in Taiwan"],"prefix":"10.1111","volume":"45","author":[{"given":"Hsing\u2010Jou","family":"Su","sequence":"first","affiliation":[{"name":"Department of Dermatology National Cheng Kung University Hospital, College of Medicine National Cheng Kung University Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"An\u2010Yu","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Dermatology National Cheng Kung University Hospital, College of Medicine National Cheng Kung University Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng\u2010Han","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Dermatology National Cheng Kung University Hospital, College of Medicine National Cheng Kung University Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia\u2010Bau","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Dermatology National Cheng Kung University Hospital, College of Medicine National Cheng Kung University Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0848-0657","authenticated-orcid":false,"given":"Chaw\u2010Ning","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology National Cheng Kung University Hospital, College of Medicine National Cheng Kung University Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4365-4533","authenticated-orcid":false,"given":"Chao\u2010Kai","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Dermatology National Cheng Kung University Hospital, College of Medicine National Cheng Kung University Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia Yu\u2010Yun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology National Cheng Kung University Hospital, College of Medicine National Cheng Kung University Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3897-6522","authenticated-orcid":false,"given":"Chao\u2010Chun","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Dermatology National Cheng Kung University Hospital, College of Medicine National Cheng Kung University Tainan Taiwan"},{"name":"International Research Center for Wound Repair and Regeneration National Cheng Kung University Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,1,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0738-081X(00)00132-2"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2010.100454"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2011.01416.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13259"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2008.00203.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2003.68"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2003.04.001"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.136833"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1807-59322008000600007"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.4081\/dr.2015.5960"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.01.056"},{"issue":"10","key":"e_1_2_7_13_1","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1258\/jrsm.96.10.516-a","article-title":"An Atlas of hair pathology\u2014with clinical correlations","volume":"96","author":"Dawber R","year":"2003","journal-title":"J R Soc Med"},{"issue":"2","key":"e_1_2_7_14_1","first-page":"235","volume":"136","author":"Sperling LC","year":"2000","journal-title":"A new look at scarring alopecia: Arch Dermatol."},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2011.05098.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13119"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2009.10.011"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.14217","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.14217","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T21:08:13Z","timestamp":1695503293000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.14217"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,16]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["10.1111\/1346-8138.14217"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.14217","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,16]]}}}