{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T22:34:01Z","timestamp":1764714841153,"version":"3.37.3"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,3,3]],"date-time":"2018-03-03T00:00:00Z","timestamp":1520035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2018,5]]},"abstract":"Abstract<\/jats:title>Palmoplantar keratodermas (PPK<\/jats:styled-content>) are heterogeneous disorders characterized by abnormal keratinization. Especially, punctate PPK<\/jats:styled-content> (PPPK<\/jats:styled-content>), one of the subtypes of hereditary PPK<\/jats:styled-content>, is a rare punctate keratoderma characterized by tiny \u201craindrop\u201d keratoses having a tendency to coalesce on the edge of soles, which are exposed to sustained pressure. If typical punctate lesions are confined to the palms and soles and the patient has a family history and late onset, it can be considered as PPPK<\/jats:styled-content> type I (PPKP<\/jats:styled-content>1), also called Buschke\u2013Fisher\u2013Brauer disease. The exact etiology of PPPK<\/jats:styled-content> has not been fully understood. Furthermore, no standardized treatment for PPPK<\/jats:styled-content> has been established and treatment options are limited. Above all, traditional systemic retinoids have been used in several cases, but dose\u2010related adverse effects are common. Therefore, combination of low\u2010dose systemic retinoids and adjuvant topical therapy can be an alternative treatment option for PPPK<\/jats:styled-content>. Herein, we report a case of PPKP<\/jats:styled-content>1 treated with combination of low\u2010dose oral acitretin (10 mg\/day) and topical salicylic acid and steroid. Despite low capacity, low\u2010dose acitretin showed excellent regression of the lesions by combined use of topical ointments. The supplementary topical therapy may be useful in reducing the dose of systemic retinoids and preventing potential toxicity.<\/jats:p>","DOI":"10.1111\/1346-8138.14255","type":"journal-article","created":{"date-parts":[[2018,3,3]],"date-time":"2018-03-03T06:28:40Z","timestamp":1520058520000},"page":"609-612","source":"Crossref","is-referenced-by-count":12,"title":["Case of punctate palmoplantar keratoderma type I treated with combination of low\u2010dose oral acitretin and topical salicylic acid and steroid"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4324-940X","authenticated-orcid":false,"given":"Jeong Won","family":"Jo","sequence":"first","affiliation":[{"name":"Department of Dermatology Gyeongsang National University School of Medicine Jinju South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Do Seon","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Dermatology Gyeongsang National University School of Medicine Jinju South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi Yeon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Gyeongsang National University School of Medicine Jinju South Korea"},{"name":"Gyeongsang Institute of Health Science Jinju South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.142.8.1076"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000468920"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foot.2012.03.004"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2004.tb00534.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.02034.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2304"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1832"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.01.909"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200708010-00001"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2444"},{"key":"e_1_2_5_12_1","first-page":"173","article-title":"Keratosis punctata palmoplantaris controlled with topical retinoids: a case report and review of the literature","volume":"74","author":"Kong MS","year":"2004","journal-title":"Cutis"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12916"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.9926"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0906-6705.2006.00435.x"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.14255","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.14255","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T12:17:04Z","timestamp":1695557824000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.14255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,3]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["10.1111\/1346-8138.14255"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.14255","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"type":"print","value":"0385-2407"},{"type":"electronic","value":"1346-8138"}],"subject":[],"published":{"date-parts":[[2018,3,3]]}}}