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These guidelines (<jats:styled-content style=\"fixed-case\">GL<\/jats:styled-content>) indicate the standard acne treatments in Japan and address pharmaceutical drugs and treatments applicable or in use in Japan. In these<jats:styled-content style=\"fixed-case\">GL<\/jats:styled-content>, the strength of the recommendation is based on clinical evidences as well as availability in Japanese medical institutions. In the 2016 and 2017<jats:styled-content style=\"fixed-case\">GL<\/jats:styled-content>, some of the clinical questions were revised, and other questions were added in accordance with approval of topical medicines containing benzoyl peroxide (<jats:styled-content style=\"fixed-case\">BPO<\/jats:styled-content>). Rather than monotherapies of antibiotics, the 2017<jats:styled-content style=\"fixed-case\">GL<\/jats:styled-content>more strongly recommend combination therapies, especially fixed\u2010dose combination gels including<jats:styled-content style=\"fixed-case\">BPO<\/jats:styled-content>in the aspects of pharmacological actions and compliance in the acute inflammatory phase to achieve earlier and better improvements. The 2017<jats:styled-content style=\"fixed-case\">GL<\/jats:styled-content>also indicate to limit the antimicrobial treatments for the acute inflammatory phase up to approximately 3 months and recommend<jats:styled-content style=\"fixed-case\">BPO<\/jats:styled-content>, adapalene, and a fixed\u2010dose combination gel of 0.1% adapalene and 2.5%<jats:styled-content style=\"fixed-case\">BPO<\/jats:styled-content>for the maintenance phase to avoid the emergence of antimicrobial\u2010resistant<jats:italic>Propionibacterium acnes<\/jats:italic>. The 2017<jats:styled-content style=\"fixed-case\">GL<\/jats:styled-content>also discuss rosacea, which requires discrimination from acne and a different treatment plan.<\/jats:p>","DOI":"10.1111\/1346-8138.14355","type":"journal-article","created":{"date-parts":[[2018,5,21]],"date-time":"2018-05-21T15:26:39Z","timestamp":1526916399000},"page":"898-935","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":69,"title":["Japanese Dermatological Association Guidelines: Guidelines for the treatment of acne vulgaris 2017"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1971-230X","authenticated-orcid":false,"given":"Nobukazu","family":"Hayashi","sequence":"first","affiliation":[{"name":"Department of Dermatology Toranomon Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirohiko","family":"Akamatsu","sequence":"additional","affiliation":[{"name":"Applied Cell and Regenerative Medicine Fujita Health University School of Medicine Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiji","family":"Iwatsuki","sequence":"additional","affiliation":[{"name":"Department of Dermatology Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryoko","family":"Shimada\u2010Omori","sequence":"additional","affiliation":[{"name":"Department of Dermatology Tohoku University Graduate School of Medicine Sendai Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chikako","family":"Kaminaka","sequence":"additional","affiliation":[{"name":"Department of Dermatology Wakayama Medical University Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1440-5178","authenticated-orcid":false,"given":"Ichiro","family":"Kurokawa","sequence":"additional","affiliation":[{"name":"Department of Dermatology Meiwa Hospital Nishinomiya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Kono","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chiba Hokusoh Hospital Nippon Medical School Inba\u2010gun Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miwa","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Kobayashi Dermatology Clinic Kitakyushu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miki","family":"Tanioka","sequence":"additional","affiliation":[{"name":"Tanioka Dermatology Clinic Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3970-9087","authenticated-orcid":false,"given":"Fukumi","family":"Furukawa","sequence":"additional","affiliation":[{"name":"Takatsuki Red Cross Hospital Takatsuki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minao","family":"Furumura","sequence":"additional","affiliation":[{"name":"Section of Dermatology Department of Medicine Fukuoka Dental College Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Yamasaki","sequence":"additional","affiliation":[{"name":"Department of Dermatology Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5495-4956","authenticated-orcid":false,"given":"Kenshi","family":"Yamasaki","sequence":"additional","affiliation":[{"name":"Department of Dermatology Tohoku University Graduate School of Medicine Sendai Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Dermatology Wakayama Medical University Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Miyachi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kyoto University Graduate School of Medicine Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Kawashima","sequence":"additional","affiliation":[{"name":"Department of Dermatology Tokyo Women's Medical University Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,5,21]]},"reference":[{"key":"e_1_2_8_19_1_2_2","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1346-8138.2007.00403.x-i1","article-title":"Kawashima M; Acne Study Group. 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