{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:39:47Z","timestamp":1787013587759,"version":"build-2736575974"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,9,6]],"date-time":"2018-09-06T00:00:00Z","timestamp":1536192000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Primary cicatricial alopecia (PCA) is a dermatological challenge. Because no large\u2010scale epidemiological study regarding PCA is available yet, we investigated the National Health Insurance Service\u2013National Sample Cohort for patients diagnosed with PCA. The annual and overall rates of incidence and prevalence of PCA during the study period (2004\u20132013) were estimated. Distribution of PCA subtypes, disease co\u2010occurrence rates and frequently prescribed medications were also evaluated. The overall incidence was 6.10 (95% confidence interval [CI], 5.62\u20136.60) per 100\u00a0000\u00a0person\u2010years. The incidence rate was stable over time (risk ratio [RR]\u00a0=\u00a01.012,\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    =\n                    <jats:italic>\u00a0<\/jats:italic>\n                    0.201) and lower in female patients (RR\u00a0=\u00a00.718,\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    &lt;\n                    <jats:italic>\u00a0<\/jats:italic>\n                    0.001). The overall prevalence was 20.93 (95% CI, 17.97\u201323.86) per 100\u00a0000 persons. The average duration of PCA was calculated as 3.23\u00a0years. Approximately 70% of the patients were below the age of 45\u00a0years. Folliculitis decalvans and dissecting cellulitis were the most common subtypes of PCA. Logistic regression analysis showed that PCA was significantly associated with thyroid disorders (adjusted odds ratio\u00a0=\u00a01.64,\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    &lt;\n                    <jats:italic>\u00a0<\/jats:italic>\n                    0.001). Clobetasol was the most frequently prescribed topical agent. Corticosteroids were the most common oral agents used, followed by tetracycline antibiotics. Our study is the first large\u2010scale study reporting the epidemiology of PCA. We found a preponderance of males and neutrophil\u2010associated subtypes of PCA, and PCA was related to thyroid disorders.\n                  <\/jats:p>","DOI":"10.1111\/1346-8138.14625","type":"journal-article","created":{"date-parts":[[2018,9,6]],"date-time":"2018-09-06T10:44:11Z","timestamp":1536230651000},"page":"1306-1311","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Primary cicatricial alopecia in a single\u2010race Asian population: A 10\u2010year nationwide population\u2010based study in South Korea"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7442-9369","authenticated-orcid":false,"given":"Jisun","family":"Yoon","sequence":"first","affiliation":[{"name":"Department of Dermatology Ajou University School of Medicine Suwon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4631-7823","authenticated-orcid":false,"given":"Jee Woong","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Ajou University School of Medicine Suwon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,9,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2012.08.016"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.09.058"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2003.04.001"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0738-081X(00)00132-2"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.10945.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.4081\/dr.2015.5960"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.12.003"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2011.66"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.08.032"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.12.007"},{"key":"e_1_2_7_12_1","first-page":"e15","article-title":"Cohort profile: the national health insurance service\u2010national sample Cohort (NHIS\u2010NSC), South Korea","volume":"46","author":"Lee J","year":"2016","journal-title":"Int J Epidemiol"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0961203309345769"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.12.038"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.04.031"},{"issue":"2","key":"e_1_2_7_16_1","first-page":"99","article-title":"Pseudopelade of Brocq is lichen planopilaris: report of four cases that support this nosology","volume":"51","author":"Silvers DN","year":"1993","journal-title":"Cutis"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.4233"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2009.03692.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2005.01.006"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0926"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.11.006"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4419-8399-2"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2011.11008"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.10.036"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.04.066"},{"issue":"4","key":"e_1_2_7_26_1","first-page":"127","article-title":"Premature androgenic alopecia and insulin resistance. Male equivalent of polycystic ovary syndrome?","volume":"39","author":"Starka L","year":"2005","journal-title":"Endocr Regul"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02763-X"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2010.10.007"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13729"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.14625","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.14625","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T10:54:38Z","timestamp":1694861678000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.14625"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,6]]},"references-count":28,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1111\/1346-8138.14625"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.14625","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,6]]},"assertion":[{"value":"2018-05-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}