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However, severely immunocompromised patients and preterm infants admitted to intensive care units are particularly at risk of developing <jats:italic>Malassezia<\/jats:italic> systemic infections. Patients often have central venous catheters which are usually the portal of entry for colonization and infection. In addition to the clinically non\u2010specific findings, a delay in the laboratorial diagnosis may occur as there is often the need to add lipid supplementation to culture in order to support these organisms\u2019 growth. Herein, we report three unrelated cases of <jats:italic>Malassezia<\/jats:italic> bloodstream infection at a university hospital during a 2\u2010year period, followed by a discussion of the clinical results and comparison with the most recently available published data on epidemiology and risk factors, pathogenesis, diagnosis, susceptibility profile and treatment.<\/jats:p>","DOI":"10.1111\/1346-8138.14653","type":"journal-article","created":{"date-parts":[[2018,9,28]],"date-time":"2018-09-28T13:58:43Z","timestamp":1538143123000},"page":"1278-1282","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["<i>Malassezia<\/i> infections with systemic involvement: Figures and facts"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5969-0235","authenticated-orcid":false,"given":"Ana Filipa","family":"Pedrosa","sequence":"first","affiliation":[{"name":"Division of Microbiology Department of Pathology Faculty of Medicine University of Porto Porto Portugal"},{"name":"Department of Dermatology and Venereology Centro Hospitalar S\u00e3o Jo\u00e3o EPE Porto Portugal"},{"name":"CINTESIS, Centre for Health Technology and Services Research Faculty of Medicine of the University of Porto Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8247-8902","authenticated-orcid":false,"given":"Carmen","family":"Lisboa","sequence":"additional","affiliation":[{"name":"Division of Microbiology Department of Pathology Faculty of Medicine University of Porto Porto Portugal"},{"name":"Department of Dermatology and Venereology Centro Hospitalar S\u00e3o Jo\u00e3o EPE Porto Portugal"},{"name":"CINTESIS, Centre for Health Technology and Services Research Faculty of Medicine of the University of Porto Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ac\u00e1cio Gon\u00e7alves","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Division of Microbiology Department of Pathology Faculty of Medicine University of Porto Porto Portugal"},{"name":"CINTESIS, Centre for Health Technology and Services Research Faculty of Medicine of the University of Porto Porto Portugal"},{"name":"Burn Unit Department of Plastic and Reconstructive Surgery Centro Hospitalar S\u00e3o Jo\u00e3o EPE Porto 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