{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T19:43:04Z","timestamp":1782330184441,"version":"3.54.5"},"reference-count":37,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2018,10,15]],"date-time":"2018-10-15T00:00:00Z","timestamp":1539561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The epidemiology of pemphigus varies among racial populations worldwide. Trends in the incidence of pemphigus have not been investigated based on the Korean National Health Insurance database. This study investigated the incidence and death rate of pemphigus with age using nationwide population data in South Korea. A nationwide population\u2010based cohort study was performed using the Korean National Health Insurance Claims Database from 2006 to 2015. The incidence of pemphigus vulgaris (<jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content>) per 1\u00a0000\u00a0000\u00a0person\u2010years was 2.059 (1.885 for males and 2.234 for females), and for pemphigus foliaceus (<jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>) 1.138 (1.205 males and 1.07 for females). The incidence of <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content> increased with age. The incidence was not different between the habitat and household income. These incidence of <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content> was significantly higher in subjects with comorbid metabolic conditions, such as diabetes mellitus, hypertension and dyslipidemia. The death rate per 1000\u00a0person\u2010years in <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content> patients increased with age after adjustment for the presence of comorbidities compared with standard death rate. This study showed that age is an important factor in <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content> patients in Korea.<\/jats:p>","DOI":"10.1111\/1346-8138.14667","type":"journal-article","created":{"date-parts":[[2018,10,15]],"date-time":"2018-10-15T10:13:51Z","timestamp":1539598431000},"page":"1396-1402","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Incidence and death rate of pemphigus vulgaris and pemphigus foliaceus in Korea: A nationwide, population\u2010based study (2006\u20132015)"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8642-2479","authenticated-orcid":false,"given":"Young Bok","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Dermatology Uijeongbu St. Mary's Hospital Uijeongbu 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