{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T21:42:42Z","timestamp":1789940562998,"version":"4.0.1"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,1,4]],"date-time":"2019-01-04T00:00:00Z","timestamp":1546560000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>An 82\u2010year\u2010old Japanese man presented with a 90\u00a0mm\u00a0\u00d7\u00a080\u00a0mm subcutaneous nodule on the left chest, not connected to the pleura, described as hypointense on T<jats:sub>1<\/jats:sub>\u2010weighted magnetic resonance imaging. Histologically, a well\u2010demarcated nodule demonstrated a patternless pattern composed of hemangiopericytoma\u2010like and short storiform patterns from the subcutis into deeper tissue. Antler\u2010like branching blood vessels and keloidal\u2010type collagen bundles were seen. Myxoid change was seen in hypocellular areas. Bizarre cells and multinucleated giant cells could be easily identified. Approximately 5 mitoses per 10 high\u2010power fields could be detected. The majority of proliferating spindle cells were positive for CD34, CD99 and BCL2 expression. Signal transducer and activator of transcription (STAT)6 was strongly expressed in the nuclei. The Ki\u201067 proliferation index was 60%. We performed wide local excision with a 30\u2010mm margin, along with resection of intercostal muscles, fasciae and periostea. Neither local recurrence nor distant metastases have occurred in 16\u00a0months of follow up. The present case is consistent with malignant solitary fibrous tumor in the subcutis histologically mimicking myxofibrosarcoma or undifferentiated pleomorphic sarcoma, definitively diagnosed by immunoexpression of STAT6. We performed a review of the published work and identified six previously reported patients with malignant superficial solitary fibrous tumor to validate the characteristics of this rare type. Four men and two women were included. The sarcomas involved the head area, trunk and thigh. Only one tumor\u2010associated death occurred despite excision and radiotherapy. Complete excision is a possible treatment choice for this tumor type.<\/jats:p>","DOI":"10.1111\/1346-8138.14755","type":"journal-article","created":{"date-parts":[[2019,1,7]],"date-time":"2019-01-07T02:33:11Z","timestamp":1546828391000},"page":"267-270","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Malignant solitary fibrous tumor in the subcutis: Report of a rare superficial malignant type and review of published work"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8608-9071","authenticated-orcid":false,"given":"Takahiro","family":"Kiyohara","sequence":"first","affiliation":[{"name":"Department of Dermatology Kansai Medical University Medical Center Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotsugu","family":"Tanimura","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kansai Medical University Medical Center Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruka","family":"Takewaki","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Kansai Medical University Medical Center Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Kansai Medical University Medical Center Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,1,4]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"385","article-title":"Primary neoplasms of the pleura: a report of five cases","volume":"11","author":"Klemperer P","year":"1931","journal-title":"Arch Pathol"},{"key":"e_1_2_5_3_1","first-page":"80","volume-title":"WHO Classification of Tumours of the Soft Tissue and Bone","author":"Fletcher CD","year":"2013"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(99)90169-7"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199812000-00007"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10328"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181a6cd33"},{"key":"e_1_2_5_8_1","first-page":"93","volume-title":"WHO Classification of Tumours of the Soft Tissue and Bone","author":"Mentzel T","year":"2013"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2522"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2509"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000137"},{"key":"e_1_2_5_12_1","first-page":"390","article-title":"Nuclear expression of STAT6 distinguishes solitary fibrous tumor from histologic mimics","volume":"27","author":"Doyle LA","year":"2014","journal-title":"Am J Surg Pathol"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001027"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2016.02.030"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12702"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199511000-00005"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1346-8138.14755","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.14755","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T05:27:16Z","timestamp":1694669236000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.14755"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,4]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1111\/1346-8138.14755"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.14755","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,4]]},"assertion":[{"value":"2018-10-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}