{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T11:04:28Z","timestamp":1774436668201,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T00:00:00Z","timestamp":1564012800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP19fk0108094"],"award-info":[{"award-number":["JP19fk0108094"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 73\u2010year\u2010old healthy woman noticed black pigmentation on both thumbnails for 6\u00a0years. Upon her visit to our clinic, she had pigmented onychomycosis with onycholysis in the distal area. There was no evidence of paronychia. Direct microscopy using Zoomblue\u2122 and histopathological examination showed aggregated blastoconidia. Fontana\u2010Masson staining confirmed fungal melanin production. A combination of morphological features and genetic testing identified the isolates as <jats:italic>Candida parapsilosis<\/jats:italic>. Fungal melanonychia due to <jats:italic>C.\u00a0parapsilosis<\/jats:italic> is rare, with only six cases reported since 1979. The minimum inhibitory concentration of the isolates was 0.25\u00a0\u03bcg\/mL for itraconazole, less than 0.03\u00a0\u03bcg\/mL for ravuconazole and 2.0\u00a0\u03bcg\/mL for terbinafine. Both oral terbinafine treatment and itraconazole pulse therapy performed for 6\u00a0months were unsuccessful. The disease was ultimately cured with a 3\u2010month treatment of oral fosravuconazole.<\/jats:p>","DOI":"10.1111\/1346-8138.15024","type":"journal-article","created":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T08:57:27Z","timestamp":1564045047000},"page":"911-913","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Fungal melanonychia caused by <i>Candida parapsilosis<\/i> successfully treated with oral fosravuconazole"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4993-304X","authenticated-orcid":false,"given":"Hiromitsu","family":"Noguchi","sequence":"first","affiliation":[{"name":"Noguchi Dermatology Clinic Kumamoto Japan"},{"name":"Ochanomizu Institute for Medical Mycology and Allergology Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadahiko","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Noguchi Dermatology Clinic Kumamoto Japan"},{"name":"Ochanomizu Institute for Medical Mycology and Allergology Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9217-1805","authenticated-orcid":false,"given":"Utako","family":"Kimura","sequence":"additional","affiliation":[{"name":"Ochanomizu Institute for Medical Mycology and Allergology Tokyo Japan"},{"name":"Department of Dermatology Juntendo University Urayasu Hospital Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masataro","family":"Hiruma","sequence":"additional","affiliation":[{"name":"Ochanomizu Institute for Medical Mycology and Allergology Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Kano","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathobiology Nihon University College of Bioresource Sciences Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Yaguchi","sequence":"additional","affiliation":[{"name":"Division of Bio\u2010resources Medical Mycology Research Center Chiba University Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0622-7682","authenticated-orcid":false,"given":"Satoshi","family":"Fukushima","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Plastic Surgery Faculty of Life Sciences Kumamoto University Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hironobu","family":"Ihn","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Plastic Surgery Faculty of Life Sciences Kumamoto University Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,7,25]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-44853-4_8"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00013-08"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3314\/mmj.17-00014"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12552"},{"key":"e_1_2_6_6_1","unstructured":"Clinical and Laboratory Standards Institute.Reference method for broth dilution antifungal susceptibility testing of yeasts: approved standard third edition M27\u2013A3.Pennsylvania:CLSI 2008."},{"key":"e_1_2_6_7_1","first-page":"11","volume-title":"Candida and Candidiasis","author":"Morgan G","year":"2012"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.2336\/nishinihonhifu.41.1075"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2000.00602.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2004.tb00624.x"},{"key":"e_1_2_6_11_1","first-page":"10","article-title":"Candida parapsilosis of the nail\u2010bed without onychomycosis","volume":"20","author":"Rieder E","year":"2014","journal-title":"Dermatol Online J"},{"key":"e_1_2_6_12_1","unstructured":"AnMK KimKH.Candida parapsilosis a rare cause of fungal melanonychia. 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