{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T07:10:54Z","timestamp":1774077054917,"version":"3.50.1"},"reference-count":45,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,8,20]],"date-time":"2019-08-20T00:00:00Z","timestamp":1566259200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The association between psoriasis and risk of atherosclerotic cardiovascular disease has not been thoroughly evaluated in a large longitudinal cohort of an Asian population. We conducted a nationwide population\u2010based retrospective cohort study encompassing more than 1.7\u00a0million Koreans with a 15\u2010year follow\u2010up period. The period prevalence of psoriasis was 0.33% among the baseline participants (1997\u20132000). In Cox proportional hazard analyses, the individuals with psoriasis had a higher adjusted hazard ratio (HR) for incidence of overall atherosclerotic cardiovascular disease (HR, 1.18; 95% confidence interval [CI], 1.09\u20131.27) compared with controls. Subgroup analyses revealed that the risk for myocardial infarction was commonly increased in both sexes with moderate to severe psoriasis (male: HR, 2.09; 95% CI, 1.35\u20133.24; female: HR, 3.23; 95% CI, 1.34\u20137.76), whereas the risk for ischemic stroke was specifically increased in female individuals with moderate to severe psoriasis (HR, 2.02; 95% CI, 1.24\u20133.30). Our data suggest that appropriate medical screening for possible cardiovascular comorbidities is warranted in Asian psoriatic patients according to disease severity and sex.<\/jats:p>","DOI":"10.1111\/1346-8138.15052","type":"journal-article","created":{"date-parts":[[2019,8,21]],"date-time":"2019-08-21T04:50:08Z","timestamp":1566363008000},"page":"859-866","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Increased risk of atherosclerotic cardiovascular disease among patients with psoriasis in Korea: A 15\u2010year nationwide population\u2010based cohort study"],"prefix":"10.1111","volume":"46","author":[{"given":"Keum Ji","family":"Jung","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Health Promotion Institute for Health Promotion Graduate School of Public Health Yonsei University Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2116-4579","authenticated-orcid":false,"given":"Tae\u2010Gyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Severance Hospital Cutaneous Biology Research Institute Yonsei University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7021-2170","authenticated-orcid":false,"given":"Jae Won","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Severance Hospital Cutaneous Biology Research Institute Yonsei University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1886-489X","authenticated-orcid":false,"given":"Minseok","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Severance Hospital Cutaneous Biology Research Institute Yonsei University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jongwook","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Dermatology Severance Hospital Cutaneous Biology Research Institute Yonsei University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang\u2010Eun","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Cardiology Severance Cardiovascular Hospital Yonsei University Health System Yonsei University College of Medicine Seoul Korea"},{"name":"Yonsei\u2010Cedars\u2010Sinai Integrative Cardiovascular Imaging Research Center Yonsei University Health System Yonsei University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyuk\u2010Jae","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Cardiology Severance Cardiovascular Hospital Yonsei University Health System Yonsei University College of Medicine Seoul Korea"},{"name":"Yonsei\u2010Cedars\u2010Sinai Integrative Cardiovascular Imaging Research Center Yonsei University Health System Yonsei University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun Ha","family":"Jee","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Health Promotion Institute for Health Promotion Graduate School of Public Health Yonsei University Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min\u2010Geol","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Severance Hospital Cutaneous Biology Research Institute Yonsei University College of Medicine Seoul Korea"},{"name":"Brain Korea 21 PLUS Project for Medical Science Yonsei University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,8,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0804595"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.339"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2017.29.4.462"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2009.59"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61909-7"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2017.07.004"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2009.03704.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.11038.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2012.04465.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2015.27.6.738"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12257"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12865"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2015.56.3.712"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13061"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2014.08.008"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.07.064"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.07.065"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.296.14.1735"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr285"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2012.02593.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12002"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.113.000062"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-016-1712-1"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.01.050"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.2.194"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.020752"},{"key":"e_1_2_7_28_1","first-page":"63","article-title":"Psoriasis and comorbidities. Epidemiological studies","author":"Egeberg A","year":"2016","journal-title":"Dan Med J"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.22.2149"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.4070\/kcj.2012.42.1.10"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.08.040"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08707.x"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04076.x"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-013-1437-3"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2010.103"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13467"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.09.021"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0007-0963.2004.05891.x"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/JID.2015.378"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2017.29.6.761"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-10556-y"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000242802.13557.2d"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199503093321003"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.199"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.114.302721"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.149"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.15052","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1346-8138.15052","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.15052","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T19:02:15Z","timestamp":1694286135000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.15052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,20]]},"references-count":45,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1111\/1346-8138.15052"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.15052","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,20]]},"assertion":[{"value":"2019-04-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}