{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:39:49Z","timestamp":1787013589809,"version":"build-2736575974"},"reference-count":18,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,5,22]],"date-time":"2020-05-22T00:00:00Z","timestamp":1590105600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Health Labor Sciences Research Grant","award":["H27-077"],"award-info":[{"award-number":["H27-077"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Hidradenitis suppurativa (HS) is a chronic relapsing skin disease localized mainly on the apocrine gland\u2010bearing areas. In Japan, HS is yet to be fully understood, and no criteria have been established for its diagnosis or severity assessment. The purpose of this study was to investigate and characterize HS in Japan. We conducted a nationwide questionnaire\u2010based study, in which Japanese diagnostic criteria were proposed. Question items included age, sex, disease duration, past history, family history, smoking status, disease severity scores (Hurley stage, modified Sartorius score and Physician Global Assessment [PGA] score), treatments, comorbidities and prognosis. We analyzed 300 patients (219 males and 81 females) diagnosed with HS based on our criteria. Average disease duration was 92.3\u00a0\u00b1\u00a06.82\u00a0months. Only 12 (4%) patients had a family history of HS. Disease severity was classified by PGA score (mild, 100 [33.3%]; moderate, 133 [44.3%]; severe, 34 [11.3%]; most severe, 29 [9.7%]) and Hurley stage (I, 69 [23%]; II, 109 [36.3%]; III, 121 [40.3%]). Disease severities based on PGA score and Hurley stage were positively correlated to modified Sartorius score using the Kruskal\u2013Wallis test (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0&lt;\u00a00.001, respectively). Patients with diabetes mellitus showed higher PGA scores (\u03c7\n                    <jats:sup>2<\/jats:sup>\n                    \u00a0=\u00a010.977,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.01185). Presence of axillary lesions related to higher PGA scores (\u03c7\n                    <jats:sup>2<\/jats:sup>\n                    \u00a0=\u00a08.6378,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.03452). The results in this study and previous studies indicate that Japanese HS patients have different backgrounds from those in Western countries, and are characterized by male predominance, higher incidence of Hurley stages II and III, higher PGA scores in patients with axillary lesions and much fewer familial cases.\n                  <\/jats:p>","DOI":"10.1111\/1346-8138.15378","type":"journal-article","created":{"date-parts":[[2020,5,22]],"date-time":"2020-05-22T06:02:52Z","timestamp":1590127372000},"page":"743-748","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Questionnaire\u2010based epidemiological study of hidradenitis suppurativa in Japan revealing characteristics different from those in Western countries"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8651-2493","authenticated-orcid":false,"given":"Koremasa","family":"Hayama","sequence":"first","affiliation":[{"name":"Division of Cutaneous Science Department of Dermatology Nihon University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8657-0618","authenticated-orcid":false,"given":"Hideki","family":"Fujita","sequence":"additional","affiliation":[{"name":"Division of Cutaneous Science Department of Dermatology Nihon University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0144-3255","authenticated-orcid":false,"given":"Takashi","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"Department of Dermatology Osaka City University Graduate School of Medicine Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadashi","family":"Terui","sequence":"additional","affiliation":[{"name":"Division of Cutaneous Science Department of Dermatology Nihon University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"The Japanese HS Research Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12966"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12881"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03356.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09198.x"},{"key":"e_1_2_7_6_1","first-page":"729","volume-title":"Dermatologic Surgery","author":"Hurley 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