{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T13:40:30Z","timestamp":1789479630952,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,5,25]],"date-time":"2020-05-25T00:00:00Z","timestamp":1590364800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Micropunch grafting is the simplest surgical intervention for refractory vitiligo but is tedious and time\u2010consuming. Therefore, we aimed to verify the efficacy and safety of dermal orientation grafting using motorized 0.5\u2010mm micropunch grafting for vitiligo. In a preliminary animal study, 12\u2010week\u2010old rats were used to observe the healing process after the transplantation of dermal orientation grafts with various punch sizes. In a clinical trial, a total of 100 vitiligo patches in 50 patients with stable vitiligo were randomly allocated to motorized 0.5\u2010mm micropunch grafting in epidermal and dermal orientations, respectively. The grafts were implanted at intervals of 5\u00a0mm at the recipient site. Treatment success was defined as greater than 75% repigmentation. In the animal study, all grafts were shown to be well integrated into the recipient site within 3\u00a0weeks. In the clinical trial, treatment success was achieved in 72% and 76% of the epidermal and dermal orientation groups, respectively; a cobblestone appearance was observed in 4% and 2%, respectively. In conclusion, we demonstrated that this new grafting method irrespective of epidermal\u2013dermal orientation using motorized 0.5\u2010mm micropunch grafting was effective and safe. We have named this the \u201cskin seeding technique\u201d and it differs from traditional punch grafting in that it can be performed regardless of the graft orientation.<\/jats:p>","DOI":"10.1111\/1346-8138.15390","type":"journal-article","created":{"date-parts":[[2020,5,26]],"date-time":"2020-05-26T05:30:15Z","timestamp":1590471015000},"page":"749-754","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Skin seeding technique with 0.5\u2010mm micropunch grafting for vitiligo irrespective of the epidermal\u2013dermal orientation: Animal and clinical studies"],"prefix":"10.1111","volume":"47","author":[{"given":"Dong Seok","family":"Kim","sequence":"first","affiliation":[{"name":"Eureka Skin &amp; Laser Clinic Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Jeong","family":"Ju","sequence":"additional","affiliation":[{"name":"Department of Dermatology St Vincent\u2019s Hospital, College of Medicine The Catholic University of Korea Suwon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han Na","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology St Vincent\u2019s Hospital, College of Medicine The Catholic University of Korea Suwon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In Hye","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Bucheon St Mary\u2019s Hospital, College of Medicine The Catholic University of Korea Bucheon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Hye","family":"Eun","sequence":"additional","affiliation":[{"name":"Department of Dermatology St Vincent\u2019s Hospital, College of Medicine The Catholic University of Korea Suwon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiehoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Dr Kim\u2019s Skin &amp; Laser Clinic Suwon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5975-8519","authenticated-orcid":false,"given":"Jung Min","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Dermatology St Vincent\u2019s Hospital, College of Medicine The Catholic University of Korea Suwon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2015.56.3.719"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14959"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2017.0002"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2019.0696"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12532"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.11197.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2016.11.009"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15411"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.01.056"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2018.4919"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.06.016"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.18950"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12730"},{"key":"e_1_2_7_15_1","first-page":"140","article-title":"Evaluation of replacement grafts and punch grafts in the treatment of vitiligo","volume":"46","author":"Kumar SA","year":"1980","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2016.1179251"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.2014.935331"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12647"},{"issue":"4","key":"e_1_2_7_19_1","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1242\/jcs.107.4.983","article-title":"E\u2010cadherin is the major mediator of human melanocyte adhesion to keratinocytes in vitro","volume":"107","author":"Tang A","year":"1994","journal-title":"J Cell Sci"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.15390","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1346-8138.15390","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.15390","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T13:03:30Z","timestamp":1693746210000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.15390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,25]]},"references-count":18,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1111\/1346-8138.15390"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.15390","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,25]]},"assertion":[{"value":"2020-03-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}