{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T07:36:58Z","timestamp":1779003418584,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T00:00:00Z","timestamp":1605657600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CMRPG1F0161"],"award-info":[{"award-number":["CMRPG1F0161"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Interdisciplinary care involving dermatologists and obstetricians is important for pregnant women with psoriasis. However, well\u2010controlled risk estimates and detailed outcome measurements for adverse pregnancy and fetal outcomes are rare and inconsistent. The aim of the present study was to investigate maternal and fetal outcomes of mothers with psoriasis by using a population\u2010based nationwide health registrar database. We identified 2\u00a0350\u00a0330 singleton pregnancies, of which 4058 singleton pregnancies were psoriatic patients using the Taiwan National Health Insurance database and birth registry from 2001 to 2012. Odds ratios (OR) and 95% confidence intervals (CI) for pregnancy outcomes were calculated using an adjusted generalized estimating equation model. Pregnancies in psoriatic patients were associated with an adjusted OR (95% CI) of 1.57 (1.31\u20131.89) for pre\u2010eclampsia, 1.5 (1.28\u20131.75) for pregnancy\u2010related hypertension and 1.57 (1.36\u20131.82) for severe post\u2010partum hemorrhage. Offspring of women with psoriasis were associated with an adjusted OR (95% CI) of 1.48 (1.11\u20131.96) for stillbirth, 1.27 (1.14\u20131.41) for low birthweight of less than 2500\u00a0g, 1.13 (1.02\u20131.25) for preterm labor, 1.12 (1.02\u20131.23) for small for gestational age and 1.09 (0.96\u20131.25) for fetal distress. Lower Apgar scores were also observed in babies born to mothers with psoriasis. In conclusion, pregnancies in women with psoriasis have a significantly higher risk of adverse pregnancy outcome compared with unaffected mothers.<\/jats:p>","DOI":"10.1111\/1346-8138.15658","type":"journal-article","created":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T10:36:00Z","timestamp":1605695760000},"page":"184-189","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Fetal\u2013neonatal and maternal outcomes in women with psoriasis vulgaris: A nationwide population\u2010based registry linkage study in Taiwan"],"prefix":"10.1111","volume":"48","author":[{"given":"Yu\u2010Huei","family":"Huang","sequence":"first","affiliation":[{"name":"Institute of Medicine Chung Shan Medical University Taichung Taiwan"},{"name":"Department of Dermatology College of Medicine Chang Gung Memorial Hospital Taoyuan Taiwan"},{"name":"School of Medicine College of Medicine Chang Gung Memorial Hospital Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7576-963X","authenticated-orcid":false,"given":"Chau","family":"Yee Ng","sequence":"additional","affiliation":[{"name":"Department of Dermatology College of Medicine Chang Gung Memorial Hospital Taoyuan Taiwan"},{"name":"School of Medicine College of Medicine Chang Gung Memorial Hospital Taoyuan Taiwan"},{"name":"Graduate Institute of Clinical Medical Sciences Chang Gung Memorial Hospital Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng\u2010Jiun","family":"Chiou","sequence":"additional","affiliation":[{"name":"Center for Artificial Intelligence in Medicine Chang Gung Memorial Hospital Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang\u2010Fu","family":"Kuo","sequence":"additional","affiliation":[{"name":"School of Medicine College of Medicine Chang Gung Memorial Hospital Taoyuan Taiwan"},{"name":"Department of Rheumatology, Allergy and Immunology Chang Gung Memorial Hospital Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,11,18]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2011.03.002"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsi.2018.06.001"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/ds.ds_28_18"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10995-006-0073-3"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2002.05543.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.07.019"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2011.271"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09899.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2923"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.02.005"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000096910"},{"issue":"3","key":"e_1_2_7_13_1","first-page":"183","article-title":"Pregnancy outcome in women with psoriasis","volume":"53","author":"Ben\u2010David G","year":"2008","journal-title":"J Reprod Med"},{"issue":"4","key":"e_1_2_7_14_1","first-page":"297","article-title":"Validation of the Taiwan Birth Registry using obstetric records","volume":"103","author":"Lin CM","year":"2004","journal-title":"J Formos Med Assoc"},{"key":"e_1_2_7_15_1","first-page":"1","article-title":"Incorporating development stratification of Taiwan townships into sampling design of large scale health interview survey","volume":"14","author":"Liu CY","year":"2006","journal-title":"J Health Manag"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(92)90133-8"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0208873"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.154.3.294"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l1656"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1994.tb02687.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20164655"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/10641950802601179"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1249366"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2010.53"},{"key":"e_1_2_7_25_1","volume-title":"Modern Epidemiology","author":"Rothman KJ","year":"2008"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.15658","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1346-8138.15658","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.15658","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,27]],"date-time":"2023-08-27T04:36:08Z","timestamp":1693110968000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.15658"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,18]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1111\/1346-8138.15658"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.15658","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,18]]},"assertion":[{"value":"2020-08-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}