{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:31:36Z","timestamp":1790962296512,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,12,11]],"date-time":"2020-12-11T00:00:00Z","timestamp":1607644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Deep cutaneous fungal infections (DCFI) are cutaneous and subcutaneous infectious diseases caused by fungi. Multiple genera of pathogenic fungi have been reported to cause DCFI. Herein, we report three rare cases of Pleosporales deep cutaneous infection in a southern Taiwan medical center. We evaluated the clinical manifestations, histopathological findings, pathogens, treatments and outcomes. The patients were a 77\u2010year\u2010old woman, a 78\u2010year\u2010old woman and an 81\u2010year\u2010old man, who lived in rural tropical areas. The lesions were erythematous noduloplaques with dark spots located on the upper extremities. Sequence\u2010based identification showed three different fungi of the order Pleosporales, namely <jats:italic>Nigrograna mackinnonii<\/jats:italic>, <jats:italic>Medicopsis romeroi<\/jats:italic> and <jats:italic>Parathyridaria percutanea<\/jats:italic>. All three cases received 200\u00a0mg of oral itraconazole daily for 10, 2 and 8\u00a0months, respectively. Two of them are free of diseases to date, and one improved partially but did not complete the treatment. Molecular tools are helpful for the identification of DCFI to exact species, which is key to successful treatment.<\/jats:p>","DOI":"10.1111\/1346-8138.15698","type":"journal-article","created":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T06:28:44Z","timestamp":1607754524000},"page":"413-417","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Deep cutaneous fungal infection by <i>Pleosporales<\/i>: An exceptional pathogen in tropical Taiwan"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9478-2733","authenticated-orcid":false,"given":"Yi\u2010Hsiang","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Dermatology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei\u2010Lun","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Research Laboratory of Medical Mycology Chang Gung Memorial Hospital Taoyuan Taiwan"},{"name":"College of Medicine Chang Gung University Taoyuan Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9804-3874","authenticated-orcid":false,"given":"Chih\u2010Hung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia\u2010Jui","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8654-0491","authenticated-orcid":false,"given":"Han\u2010Chi","family":"Tseng","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 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