{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:59:05Z","timestamp":1787497145875,"version":"build-2736575974"},"reference-count":36,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,2,24]],"date-time":"2021-02-24T00:00:00Z","timestamp":1614124800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Hidradenitis suppurativa (HS), also called acne inversa, is an inflammatory skin disease, which causes HS patients to suffer from recurrent symptoms and severe comorbidities. The aim of this article was to provide evidence on the epidemiology of HS in Taiwan through a retrospective population\u2010based cohort study. The patients with International Classification of Diseases, Ninth Revision, Clinical Modification code 705.83 and Anatomical Therapeutic Chemical codes for HS treatments from 2000 to 2013 in the National Health Insurance Research Database, which covers 99.9% Taiwanese residents, were enrolled in this 14\u2010year nationwide population\u2010based cohort study. The age\u2010 and sex\u2010standardized prevalence, incidence, and the prescription pattern for HS were analyzed. The annual percent change (APC) was used to estimate the trend of prevalence and incidence of HS from 2000 to 2013. During 2000\u20132013 in Taiwan, the 14\u2010year period prevalence rate was 185.6\/100\u00a0000 (95% confidence interval [CI], 177.3\u2013194.3) with an APC of \u20132.96% (95% CI, \u22121.73 to \u22124.17) and the mean annual adjusted incidence rate from 2001 to 2013 was 11.8\/100\u00a0000 (95% CI, 11.2\u201312.5) with an APC of \u22124.65% (95% CI, \u22123.32 to \u22125.95). Female\u00a0:\u00a0male ratio was 0.92 and the most common onset age was 15\u201324\u00a0years. Major treatments were systemic corticosteroids, systemic antihistamines, systemic antibiotics, and topical antibiotics. An increasing tendency of using systemic antibiotics was noted. In Taiwan, decreasing incidence and prevalence of HS was shown during 2000\u20132013. Relatively lower incidence and prevalence were noted compared to Western countries. Male predominance was revealed, and the use of systemic antibiotics became the mainstream in treatment for HS.<\/jats:p>","DOI":"10.1111\/1346-8138.15811","type":"journal-article","created":{"date-parts":[[2021,2,24]],"date-time":"2021-02-24T12:52:34Z","timestamp":1614171154000},"page":"613-619","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Epidemiology of hidradenitis suppurativa in Taiwan: A 14\u2010year nationwide population\u2010based study"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5950-0064","authenticated-orcid":false,"given":"Yun\u2010Tzu","family":"Liang","sequence":"first","affiliation":[{"name":"School of Medicine Chung Shan Medical University Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih\u2010Jung","family":"Yeh","sequence":"additional","affiliation":[{"name":"Department of Public Health Chung Shan Medical University Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing\u2010Yang","family":"Huang","sequence":"additional","affiliation":[{"name":"Institute of Medicine College of Medicine Chung Shan Medical University Taichung Taiwan"},{"name":"Center for Health Data Science Chung Shan Medical University Hospital Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0310-2769","authenticated-orcid":false,"given":"James Cheng\u2010Chung","family":"Wei","sequence":"additional","affiliation":[{"name":"Institute of Medicine College of Medicine Chung Shan Medical University Taichung Taiwan"},{"name":"Department of Allergy, Immunology &amp; Rheumatology Chung Shan Medical University Hospital Taichung Taiwan"},{"name":"Graduate Institute of Integrated Medicine China Medical University Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S111019"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41702-019-0052-0"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-020-00504-4"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16101"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15940"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.02.005"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.02.067"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.16691"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12966"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13041"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000468148"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.04.067"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2018.2117"},{"key":"e_1_2_7_15_1","first-page":"1","article-title":"Hidradenitis suppurativa in Sweden: a registry\u2010based cross\u2010sectional study of 13,538 patients","volume":"3","author":"Killasli H","year":"2020","journal-title":"Dermatology"},{"key":"e_1_2_7_16_1","unstructured":"https:\/\/www.hpa.gov.tw\/.Taiwan: Health Promotion Administration Ministry of Health and Welfare; c2001\u201007 [Cited 2020 Nov 23].https:\/\/www.hpa.gov.tw\/EngPages\/Detail.aspx?nodeid=1062&pid=6073."},{"key":"e_1_2_7_17_1","unstructured":"http:\/\/www.endo\u2010dm.org.tw\/.Taiwan: The Diabetes Association of the Republic of China; c1980\u201003 [Cited 2020 Nov 23].http:\/\/www.endo\u2010dm.org.tw\/dia\/english\/about\/history.asp."},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2017.0201"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(96)90321-7"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.04.001"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0929-6646(09)60161-3"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.4103\/TPSY.TPSY_26_19"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.15378"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15071"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1159\/000481836"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2009.11.052"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14038"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2012.01552.x"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2015.08.006"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2011.1950"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-33101-8_18"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/11.6.954"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.14656"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.11.911"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-017-0280-2"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.3109\/09546634.2010.509383"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.5070\/D35VW402NF"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.15811","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1346-8138.15811","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.15811","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T09:45:02Z","timestamp":1693561502000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.15811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,24]]},"references-count":36,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1111\/1346-8138.15811"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.15811","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,24]]},"assertion":[{"value":"2020-09-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}