{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T17:32:39Z","timestamp":1763141559529,"version":"3.40.5"},"reference-count":14,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T00:00:00Z","timestamp":1619481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Dermoscopic images of pigmented lesions have distinct features on the sole where skin ridges and furrows exist. Pigmentation of benign nevus usually locates on the skin furrow, while the malignant melanoma is pigmented on the skin ridge. Correspondence between dermoscopy and pathology in the pigmented lesions on soles have been studied based on conventional vertical pathological images. However, for the full understanding of the correspondence, observation of horizontal histological images would be required, because the epidermis constructs unique horizontal structures, namely crista profunda limitans, crista profunda intermedia, and transverse ridge. In this study, we analyzed basic dermoscopic images of the representative acral melanocytic lesions (nevus, lentigo, and malignant melanoma) by horizonal histological images. We created serial horizontal pathological images by digital reconstruction of a hundred of serial vertical images. We could show that parallel furrow pattern is created by the pigmentation of crista profunda limitans, parallel ridge pattern by the pigmentation of both of crista profunda limitans and crista profunda intermediate, and lattice\u2010like pattern by the pigmentation of transverse ridge. Our results would be useful for the intuitive histological understanding of dermoscopy.<\/jats:p>","DOI":"10.1111\/1346-8138.15907","type":"journal-article","created":{"date-parts":[[2021,4,28]],"date-time":"2021-04-28T06:55:35Z","timestamp":1619592935000},"page":"1193-1200","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Three\u2010dimensional histological explanation of the dermoscopy patterns in acral melanocytic lesions"],"prefix":"10.1111","volume":"48","author":[{"given":"Pawit","family":"Phadungsaksawasdi","sequence":"first","affiliation":[{"name":"Department of Dermatology Hamamatsu University School of Medicine Hamamatsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2107-9091","authenticated-orcid":false,"given":"Akira","family":"Kasuya","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hamamatsu University School of Medicine Hamamatsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4547-2277","authenticated-orcid":false,"given":"Kensuke","family":"Fukuchi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hamamatsu University School of Medicine Hamamatsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Aoshima","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hamamatsu University School of Medicine Hamamatsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinsuke","family":"Nakazawa","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hamamatsu University School of Medicine Hamamatsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hamamatsu University School of Medicine Hamamatsu Japan"},{"name":"Dr. Phillip Frost Department of Dermatology &amp; Cutaneous Surgery University of Miami Miller School of Medicine Miami USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiharu","family":"Fujiyama","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hamamatsu University School of Medicine Hamamatsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7452-6919","authenticated-orcid":false,"given":"Yoshiki","family":"Tokura","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hamamatsu University School of Medicine Hamamatsu Japan"},{"name":"Department of Cellular &amp; Molecular Anatomy Hamamatsu University School of Medicine Hamamatsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuya","family":"Honda","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hamamatsu University School of Medicine Hamamatsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,4,27]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_6_2_1","DOI":"10.1001\/archderm.134.12.1563"},{"doi-asserted-by":"publisher","key":"e_1_2_6_3_1","DOI":"10.1016\/j.jaad.2005.04.045"},{"doi-asserted-by":"publisher","key":"e_1_2_6_4_1","DOI":"10.1038\/s41598-019-56522-8"},{"doi-asserted-by":"publisher","key":"e_1_2_6_5_1","DOI":"10.1111\/jdv.15895"},{"doi-asserted-by":"publisher","key":"e_1_2_6_6_1","DOI":"10.1111\/bjd.17819"},{"doi-asserted-by":"publisher","key":"e_1_2_6_7_1","DOI":"10.1016\/j.jaad.2015.12.038"},{"doi-asserted-by":"publisher","key":"e_1_2_6_8_1","DOI":"10.1111\/j.1346-8138.2010.01174.x"},{"key":"e_1_2_6_9_1","first-page":"181","article-title":"Dermoscopy basics and melanocytic lesions","volume":"21","author":"Tanaka M","year":"2013","journal-title":"Hong Kong J Dermatol Venereol"},{"doi-asserted-by":"publisher","key":"e_1_2_6_10_1","DOI":"10.1016\/j.jaad.2019.01.081"},{"doi-asserted-by":"publisher","key":"e_1_2_6_11_1","DOI":"10.1001\/archderm.140.10.1233"},{"doi-asserted-by":"publisher","key":"e_1_2_6_12_1","DOI":"10.1001\/archderm.143.11.1423"},{"doi-asserted-by":"publisher","key":"e_1_2_6_13_1","DOI":"10.26420\/austinjdermatolog.2017.1076"},{"doi-asserted-by":"publisher","key":"e_1_2_6_14_1","DOI":"10.1111\/j.1346-8138.2010.01152.x"},{"doi-asserted-by":"publisher","key":"e_1_2_6_15_1","DOI":"10.1038\/jid.2009.146"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.15907","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1346-8138.15907","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.15907","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T23:27:45Z","timestamp":1693351665000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.15907"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,27]]},"references-count":14,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1111\/1346-8138.15907"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.15907","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"type":"print","value":"0385-2407"},{"type":"electronic","value":"1346-8138"}],"subject":[],"published":{"date-parts":[[2021,4,27]]},"assertion":[{"value":"2020-12-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}