{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:06:10Z","timestamp":1791237970707,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,4,24]],"date-time":"2021-04-24T00:00:00Z","timestamp":1619222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Dermoscopy is an efficient and non\u2010invasive technique which has been widely used in the diagnosis of nail disorders including nail psoriasis (NP). Many nail dermoscopic features are considered as clues to NP. The aim of this study was to investigate specific dermoscopic features of fingernail psoriasis and the correlation between the severity of nail lesions or systemic inflammation, and psoriasis severity of skin and nail. This observational study recruited 135 patients with fingernail psoriasis (1186 fingernails) and 30 patients with onychomycosis (80 fingernails). All of the involved fingernails were examined with a handheld dermatoscope. The Nail Psoriasis Severity Index score (NAPSI) score, Psoriasis Area and Severity Index (PASI) score, body surface area (BSA), and detailed history of patients with psoriasis were recorded. Mann\u2013Whitney<jats:italic>U<\/jats:italic>\u2010test, \u03c7<jats:sup>2<\/jats:sup>\u2010test, Spearman\u2019s correlation, and Kruskal\u2013Wallis H\u2010test were used for statistical analysis, and the significance threshold was<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05. The trial registration number was 2020\u2010SR\u2010045. We identified onycholysis as the most common feature (93.3%) of fingernail psoriasis. Red lunula, longitudinal fissures, transverse grooves, nail plate crumbling, trachyonychia, oil\u2010dropping sign, erythematous border of an onycholytic area, subungual hyperkeratosis, and dilated streaky capillaries were relevant to NP severity (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05). Red lunula, transverse grooves, nail plate crumbling, trachyonychia, oil\u2010dropping sign, erythematous border of an onycholytic area, splinter hemorrhages, and dilated streaky capillaries were relevant to systemic inflammation severity (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05). The total NAPSI score was positively associated with the PASI score and BSA (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.0001). The thumb had a higher NAPSI score than the other fingers (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05). In conclusion, dermoscopic features can improve the accuracy of diagnosis of nail psoriasis, and have correlations with psoriasis severity.<\/jats:p>","DOI":"10.1111\/1346-8138.15908","type":"journal-article","created":{"date-parts":[[2021,4,24]],"date-time":"2021-04-24T16:09:37Z","timestamp":1619280577000},"page":"894-901","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Dermoscopic features of nail psoriasis: Positive correlation with the severity of psoriasis"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3630-7883","authenticated-orcid":false,"given":"FangYuan","family":"Long","sequence":"first","affiliation":[{"name":"Department of Dermatology First Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ZhiQin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Dermatology First Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"He","sequence":"additional","affiliation":[{"name":"Department of Dermatology First Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5438-3604","authenticated-orcid":false,"given":"Jie","family":"Tu","sequence":"additional","affiliation":[{"name":"Department of Dermatology First Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Dermatology First Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JiPing","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Dermatology First Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7159-879X","authenticated-orcid":false,"given":"Yan","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Dermatology First Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6510-1051","authenticated-orcid":false,"given":"ZhiQiang","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Dermatology First Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,4,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.07.073"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/180496"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.24172"},{"issue":"8","key":"e_1_2_7_5_1","first-page":"1752","article-title":"Baseline relationships between psoriasis and psoriatic arthritis: analysis of 221 patients with active psoriatic arthritis. Department of Veterans Affairs Cooperative Study Group on Seronegative Spondyloarthropathies","volume":"26","author":"Cohen MR","year":"1999","journal-title":"J Rheumatol"},{"issue":"2","key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"187","DOI":"10.4103\/idoj.IDOJ_272_19","article-title":"The impact of onychopathies on quality of life: a hospital\u2010based, cross\u2010sectional Study","volume":"11","author":"Tabassum H","year":"2020","journal-title":"Indian Dermatol Online J"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2147\/PTT.S126281"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000316179"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10227-002-0143-0"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2013.06.016"},{"issue":"5","key":"e_1_2_7_11_1","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1684\/ejd.2018.3396","article-title":"The value of (video)dermoscopy in the diagnosis and monitoring of common inflammatory skin diseases: a systematic review","volume":"28","author":"Vos M","year":"2018","journal-title":"Eur J Dermatol"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15344"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12354"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1505557"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15035"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.144.6.828"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2008.34293.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.01.072"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0190-9622(03)00910-1"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.156377"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.5114\/ada.2017.65618"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13752"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12218"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10579.x"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.3233\/CH-131766"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.14151"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2010.04720.x"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.5826\/dpc.0804a06"},{"issue":"1","key":"e_1_2_7_29_1","doi-asserted-by":"crossref","first-page":"35","DOI":"10.4103\/idoj.IDOJ_51_19","article-title":"Comparative study of clinical and dermoscopic features in nail psoriasis","volume":"11","author":"Wanniang N","year":"2020","journal-title":"Indian Dermatol Online J"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.19466"},{"issue":"5","key":"e_1_2_7_31_1","first-page":"872","article-title":"Vascularity of nail bed by ultrasound to discriminate psoriasis, psoriatic arthritis and healthy controls","volume":"35","author":"Aydin SZ","year":"2017","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.170962"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.11.026"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1159\/000246274"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.07.042"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hcl.2008.03.010"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.15908","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1346-8138.15908","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.15908","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,2]],"date-time":"2023-11-02T17:41:10Z","timestamp":1698946870000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.15908"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,24]]},"references-count":35,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1111\/1346-8138.15908"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.15908","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,24]]},"assertion":[{"value":"2020-10-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}