{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:49:41Z","timestamp":1790423381129,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,8,30]],"date-time":"2021-08-30T00:00:00Z","timestamp":1630281600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HI14C2686"],"award-info":[{"award-number":["HI14C2686"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HI17C1659"],"award-info":[{"award-number":["HI17C1659"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The association between psoriasis and risk of psychiatric diseases has not been thoroughly evaluated in a large longitudinal cohort of the Asian population. We conducted a nationwide cohort study encompassing more than 1.6\u00a0million Koreans with a 12\u2010year follow\u2010up period. Patients were considered to be in the psoriasis cohort if they had an incident diagnostic code for psoriasis and included patients were followed up until they developed any psychiatric disease. In adjusted models, psoriasis patients (n\u00a0=\u00a010\u00a0868) were at an 18% increased risk for depression (hazard ratio [HR], 1.18; 95% confidence interval [CI], 1.09\u20131.26), 16% for anxiety disorders (HR, 1.16; 95% CI, 1.08\u20131.26), and 21% for somatoform disorders (HR, 1.21; 95% CI, 1.08\u20131.34) compared with the referent cohort (<jats:italic>n<\/jats:italic>\u00a0=\u00a01\u00a0620\u00a0055). Patients with moderate\u2010to\u2010severe psoriasis had a higher risk of developing depression and somatoform disorders than patient with mild disease (depression, HR, 1.28; 95% CI, 1.07\u20131.54 vs HR, 1.17; 95% CI, 1.07\u20131.27; somatoform disorders, HR, 1.60; 95% CI, 1.26\u20132.03 vs HR, 1.13; 95% CI, 1.00\u20131.28). Our results highlight the burden of psychiatric diseases in patients with psoriasis in Korea and suggest that appropriate medical support for possible mental illness is warranted in Asian psoriatic patients.<\/jats:p>","DOI":"10.1111\/1346-8138.16115","type":"journal-article","created":{"date-parts":[[2021,8,31]],"date-time":"2021-08-31T06:32:28Z","timestamp":1630391548000},"page":"1763-1771","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Risk of psychiatric diseases among patients with psoriasis in Korea: A 12\u2010year nationwide population\u2010based cohort study"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8516-7894","authenticated-orcid":false,"given":"Jongwook","family":"Oh","sequence":"first","affiliation":[{"name":"Department of Dermatology Severance Hospital Cutaneous Biology Research Institute Yonsei University College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keum Ji","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Health Promotion Institute for Health Promotion Graduate School of Public Health Yonsei University Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2116-4579","authenticated-orcid":false,"given":"Tae\u2010Gyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Severance Hospital Cutaneous Biology Research Institute Yonsei University College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hae Won","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Medical Education Yonsei University College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun Ha","family":"Jee","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Health Promotion Institute for Health Promotion Graduate School of Public Health Yonsei University Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min\u2010Geol","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Severance Hospital Cutaneous Biology Research Institute Yonsei University College of Medicine Seoul South 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