{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T21:27:25Z","timestamp":1771104445394,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,10,24]],"date-time":"2021-10-24T00:00:00Z","timestamp":1635033600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Effective vaccines for prevention of severe course and lethal outcome of coronavirus disease 2019 have been developed and approved in regulatory rolling and fast\u2010track procedures; they are now widely distributed worldwide. Data about cutaneous side\u2010effects of the new mRNA\u2010type vaccines is scant, however. We herein report two similar cases of cutaneous adverse drug reactions (ADR) mimicking Rowell\u2019s syndrome that occurred after the first dose of BNT162b2 and mRNA\u20101273, respectively. Both patients achieved prompt clinical improvement with a short pulse of oral prednisolone and non\u2010steroidal inflammatory drugs. We suspect this phenomenon to occur in a timeframe of 7\u201314\u00a0days after vaccination due to an interferon\u2010\u03b3\u2010driven shift towards type I immunity in susceptible individuals. As rheumatic patients were excluded from phase III clinical trials and as most countries prioritized the elderly population to receive the vaccinations first, cutaneous ADR might become more frequent once the younger part of the population is vaccinated over the course of 2021. Atypical cutaneous ADR might be misinterpreted or overlooked by non\u2010dermatologists. Further studies are required to determine the best suitable vaccine types for individual groups of patients.<\/jats:p>","DOI":"10.1111\/1346-8138.16210","type":"journal-article","created":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T04:47:51Z","timestamp":1635137271000},"page":"151-156","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Annular plaques mimicking Rowell\u2019s syndrome in the course of coronavirus disease 2019 mRNA vaccines: An overlooked phenomenon?"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2069-0486","authenticated-orcid":false,"given":"Dennis","family":"Niebel","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy University Hospital Bonn  Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasmin","family":"Wilhelmi","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy University Hospital Bonn  Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luka","family":"De Vos","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy University Hospital Bonn  Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana","family":"Ziob","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy University Hospital Bonn  Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristel","family":"Jaschke","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy University Hospital Bonn  Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Bieber","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy University Hospital Bonn  Bonn 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